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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00758


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00758
General rule information [?]

Accession PRU00758
Dates 23-APR-2009 (Created)
31-JAN-2025 (Last updated, Version 10)
Data class Domain;
Predictors PROSITE; PS51424; ROC
Name Small GTPase superfamily. Roc family
Function Small GTPase domain found always associated to a COR domain.
Scope(s) Eukaryota
Example(s) Q8MVR1;

Propagated annotation [?]

Keywords [?]

GTP-binding
Hydrolase
Nucleotide-binding

Gene Ontology [?]

GO:0005525; Molecular function:GTP binding
GO:0003924; Molecular function:GTPase activity
GO:0007264; Biological process:small GTPase-mediated signal transduction
GO:0007165; Biological process:signal transduction

Features [?]

From: PS51424
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Roc #"
BINDING 14 21 /ligand="GTP"
/ligand_id="ChEBI:CHEBI:37565"
BINDING 65 69 /ligand="GTP"
/ligand_id="ChEBI:CHEBI:37565"
BINDING 124 127 /ligand="GTP"
/ligand_id="ChEBI:CHEBI:37565"

Additional information [?]

Size range unlimited amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]