PRU00766

General rule information [?]

Accession	PRU00766
Dates	23-MAR-2012 (Created) 21-NOV-2019 (Last updated, Version 6)

Data class

Domain

Predictors

PROSITE; PS51436; POTYVIRUS_NIA_PRO

Name	Potyvirus NIa protease (NIa-pro) domain

Function

The potyvirus NIa-pro has a His-Asp-Cys catalytic triad, which is homologous to the trypsin-like proteases except for Cys replacing Ser.

Propagated annotation [?]

Gene Ontology [?]

case <FTGroup:1>

GO:0016787; Molecular function: hydrolase activity.
GO:0008233; Molecular function: peptidase activity.
GO:0006508; Biological process: proteolysis.
GO:0004197; Molecular function: cysteine-type endopeptidase activity.

Keywords [?]

Hydrolase
Protease
Thiol protease

end case

Features [?]

From: PS51436

Key From To Description Tag Condition FTGroup

DOMAIN from to Peptidase C4 #

ACT_SITE 46 46 For nuclear inclusion protein A activity H 1

ACT_SITE 81 81 For nuclear inclusion protein A activity D 1

ACT_SITE 151 151 For nuclear inclusion protein A activity C 1

Additional information [?]

Size range	942-3491 amino acids
Related rules	None
Repeats	1
Topology	Undefined
Example	P89509 (POLG_TUMVJ)
Scope	Viruses; Potyviridae
Comments	None

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

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UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets

Viruses [38]
Retrieve set of proteins with 3D structure for this domain