ProRule PRU00766

General rule information [?]

Accession PRU00766
Dates 23-MAR-2012 (Created)
21-NOV-2019 (Last updated, Version 6)
Data class Domain;
Name Potyvirus NIa protease (NIa-pro) domain
Function The potyvirus NIa-pro has a His-Asp-Cys catalytic triad, which is homologous to the trypsin-like proteases except for Cys replacing Ser.
Scope(s) Viruses
Example(s) P89509 (POLG_TUMVJ);

Propagated annotation [?]

Keywords [?]

Gene Ontology [?]

case <FTGroup:1>
GO:0016787; Molecular function:hydrolase activity
GO:0008233; Molecular function:peptidase activity
GO:0006508; Biological process:proteolysis
GO:0004197; Molecular function:cysteine-type endopeptidase activity

Features [?]

From: PS51436
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Peptidase C4 #"
ACT_SITE 46 46 /note="For nuclear inclusion protein A activity" H 1
ACT_SITE 81 81 /note="For nuclear inclusion protein A activity" D 1
ACT_SITE 151 151 /note="For nuclear inclusion protein A activity" C 1

Additional information [?]

Size range 942-3491 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


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UniProtKB rule member sequences [?]