We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU00769
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00769
General rule information
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| Accession | PRU00769 |
| Dates | 08-APR-2009 (Created)
21-NOV-2019 (Last updated, Version 6) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51438; ALBUMIN_2 |
Name | Albumin domain |
| Function | A domain consisting of 10 alpha-helices found in serum transport proteins. |
| Scope(s) |
Eukaryota Vertebrata |
| Example(s) | P49822; |
Propagated annotation
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Comments
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| SUBCELLULAR LOCATION | Secreted. |
| SIMILARITY | Belongs to the ALB/AFP/VDB family. |
Keywords
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| Secreted | |
| case <FTTag:disulf> | |
| Disulfide bond | |
| end case | |
Gene Ontology
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| GO:0005576; Cellular component:extracellular region |
Features
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| From: PS51438 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="Albumin #" | |||||||||
| DISULFID | 14 | 60 | disulf | C-x*-C | ||||||||
| DISULFID | 59 | 67 | disulf | C-x*-C | ||||||||
| DISULFID | 83 | 100 | disulf | C-x*-C | ||||||||
| DISULFID | 99 | 110 | disulf | C-x*-C | ||||||||
| DISULFID | 137 | 182 | disulf | C-x*-C | ||||||||
| DISULFID | 181 | 190 | disulf | C-x*-C | ||||||||
Additional information
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| Size range | 30-230 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1-7 |
| Topology | Not cytoplasmic |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [49] All [ 49 ]
- Retrieve set of proteins with 3D structure for this domain