PRU00783

General rule information [?]

Accession	PRU00783
Dates	19-JUN-2009 (Created) 19-NOV-2022 (Last updated, Version 8)

Data class

Domain

Predictors

PROSITE; PS50146; DAGK

Names

DAG-kinase catalytic (DAGKc) domain; diacylglycerol kinase catalytic domain; DGK C4-a domain; DgkB domain 1

Function

The DAG-kinase catalytic domain (DAGKc) is present in mammalian lipid kinases, such as diacylglycerol (DAG), ceramide and sphingosine kinases, as well as in related bacterial lipid kinases.

Propagated annotation [?]

Description [?]

+ RecName: EC 2.7.-.-;

Gene Ontology [?]

GO:0016740; Molecular function: transferase activity.
GO:0016301; Molecular function: kinase activity.

case <FTGroup:1>

GO:0005524; Molecular function: ATP binding.

Keywords [?]

ATP-binding

end case

Kinase
Transferase

Features [?]

From: PS50146

Key From To Description Tag Condition FTGroup

DOMAIN from to DAGKc #

BINDING 11 15 /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616 1

BINDING 69 75 /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616 1

BINDING 43 43 /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616 [ST] 1

BINDING 100 100 /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616 [ST] 1

Additional information [?]

Size range	110-195 amino acids
Related rules	None
Repeats	1
Topology	Undefined
Examples	Q6GFF9 (DAGK_STAAR); Q87ZA2 (YEGS_PSESM); Q03603 (DGK3_CAEEL): [Recover all]
Scope	Bacteria Eukaryota Archaea
Comments	None

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

View rule in raw text format (no links)

UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets

Bacteria [125]

Eukaryota [76]

All [ 201 ]
Retrieve set of proteins with 3D structure for this domain

Bacteria	[125]
Eukaryota	[76]
All	[ 201 ]