ProRule PRU00793
General rule information
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Accession | PRU00793 |
Dates | 27-JUL-2009 (Created)
21-NOV-2019 (Last updated, Version 8) |
Data class | Domain; |
Predictors |
PROSITE; PS51461; NC1_FIB |
Name | Fibrillar collagen C-terminal non-collagenous (NC1) domain |
Function | The NC1 domain is the most conserved part of fibrillar collagens from invertebrates to vertebrates (types I-III, V, XI, XXIV and XXVII). |
Scope(s) |
Eukaryota |
Example(s) | P02452 (CO1A1_HUMAN); |
Propagated annotation
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Comments
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case <OC:Metazoa> | |
SUBCELLULAR LOCATION | Secreted, extracellular space, extracellular matrix. |
end case | |
case <OC:Metazoa> | |
SIMILARITY | Belongs to the fibrillar collagen family. |
Keywords
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Gene Ontology
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GO:0005615; Cellular component:extracellular space |
GO:0005201; Molecular function:extracellular matrix structural constituent |
Features
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From: PS51461 | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
DOMAIN | from | to | /note="Fibrillar collagen NC1 #" | |||||||||
DISULFID | 31 | 31 | /note="Interchain" | disulf | C | |||||||
DISULFID | 37 | 37 | /note="Interchain" | disulf | C | |||||||
DISULFID | 54 | 54 | /note="Interchain" | disulf | C | |||||||
DISULFID | 63 | 63 | /note="Interchain" | disulf | C | |||||||
DISULFID | 72 | 225 | disulf | C-x*-C | ||||||||
DISULFID | 133 | 178 | disulf | C-x*-C |
Additional information
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Size range | 185-251 amino acids |
Related rules |
None |
Fusion | None |
Repeats | 1-4 |
Topology | Not cytoplasmic |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [60] All [ 60 ]
- Retrieve set of proteins with 3D structure for this domain