ProRule PRU00793

General rule information [?]

Accession PRU00793
Dates 27-JUL-2009 (Created)
21-NOV-2019 (Last updated, Version 8)
Data class Domain;
Predictors PROSITE; PS51461; NC1_FIB
Name Fibrillar collagen C-terminal non-collagenous (NC1) domain
Function The NC1 domain is the most conserved part of fibrillar collagens from invertebrates to vertebrates (types I-III, V, XI, XXIV and XXVII).
Scope(s) Eukaryota
Example(s) P02452 (CO1A1_HUMAN);

Propagated annotation [?]

Comments [?]

case <OC:Metazoa>
SUBCELLULAR LOCATIONSecreted, extracellular space, extracellular matrix.
end case
case <OC:Metazoa>
SIMILARITYBelongs to the fibrillar collagen family.

Keywords [?]

Gene Ontology [?]

GO:0005615; Cellular component:extracellular space
GO:0005201; Molecular function:extracellular matrix structural constituent

Features [?]

From: PS51461
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Fibrillar collagen NC1 #"
DISULFID 31 31 /note="Interchain" disulf C
DISULFID 37 37 /note="Interchain" disulf C
DISULFID 54 54 /note="Interchain" disulf C
DISULFID 63 63 /note="Interchain" disulf C
DISULFID 72 225 disulf C-x*-C
DISULFID 133 178 disulf C-x*-C

Additional information [?]

Size range 185-251 amino acids
Related rules None
Fusion None
Repeats 1-4
Topology Not cytoplasmic


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

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UniProtKB rule member sequences [?]