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annotation rule: PRU00793

General rule information [?]

Accession PRU00793
Dates 27-JUL-2009 (Created)
21-NOV-2019 (Last updated, Version 8)
Data class Domain
Predictors PROSITE; PS51461; NC1_FIB
Name Fibrillar collagen C-terminal non-collagenous (NC1) domain
Function The NC1 domain is the most conserved part of fibrillar collagens from invertebrates to vertebrates (types I-III, V, XI, XXIV and XXVII).

Propagated annotation [?]


Comments [?]

case <OC:Metazoa>
Subcellular location Secreted, extracellular space, extracellular matrix.
end case

case <OC:Metazoa>
Similarity Belongs to the fibrillar collagen family.

Gene Ontology [?]

GO:0005615; Cellular component: extracellular space.
GO:0005201; Molecular function: extracellular matrix structural constituent.

Keywords [?]

Collagen
Extracellular matrix
Secreted
end case

case <FTTag:disulf>
Disulfide bond
end case


Features [?]

From: PS51461
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       Fibrillar collagen NC1 #        
DISULFID     31     31       Interchain   disulf   C  
DISULFID     37     37       Interchain   disulf   C  
DISULFID     54     54       Interchain   disulf   C  
DISULFID     63     63       Interchain   disulf   C  
DISULFID     72     225           disulf   C-x*-C  
DISULFID     133     178           disulf   C-x*-C  

Additional information [?]

Size range 185-251 amino acids
Related rules None
Repeats 1-4
Topology Not cytoplasmic
Example P02452 (CO1A1_HUMAN)
Scope
Eukaryota
Comments None

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.


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UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets
Eukaryota [49]