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annotation rule: PRU00794

General rule information [?]

Accession PRU00794
Dates 2-OCT-2009 (Created)
16-DEC-2016 (Last updated, Version 3)
Data class Domain
Predictors PROSITE; PS51462; NUDIX
Name Nudix hydrolase domain
Function The Nudix superfamily is widespread among eucaryotes, bacteria, archaea and viruses and consists mainly of pyrophosphohydrolases that act upon substrates of general structure NUcleoside DIphosphate linked to another moiety, X (NDP-X) to yield NMP plus P-X.

Propagated annotation [?]


Cross-references [?]

PROSITE PS00893; NUDIX_BOX; 1;
PS01293; NUDIX_COA; 0-1;

Gene Ontology [?]

GO:0016787; Molecular function: hydrolase activity.
GO:0046872; Molecular function: metal ion binding.

Keywords [?]


Features [?]

From: PS51462
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       Nudix hydrolase #        
MOTIF     36     57       Nudix box #        

Additional information [?]

Size range 105-260 amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q5RD76 (NUD12_PONAB)
Scope
Eukaryota
Bacteria
Archaea
Viruses
Comments None

Copyright

PROSITE is copyright. It is produced by the SIB Swiss Institute Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified. Usage by and for commercial entities requires a license agreement. For information about the licensing scheme send an email to license@isb-sib.ch or see: prosite_license.html.



UniProtKB rule member sequences [?]