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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00814


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00814
General rule information [?]

Accession PRU00814
Dates 06-MAY-2010 (Created)
19-NOV-2022 (Last updated, Version 9)
Data class Domain;
Predictors PROSITE; PS51481; DHAK
Name DhaK domain
Function The DhaK domain is the dihydroxyacetone- (Dha-)binding domain of Dha kinases.
Scope(s) Eukaryota
Bacteria
Example(s) P76015;

Propagated annotation [?]

Keywords [?]

Kinase
Transferase

Gene Ontology [?]

GO:0016301; Molecular function:kinase activity
GO:0016740; Molecular function:transferase activity

Features [?]

From: PS51481
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="DhaK #"
ACT_SITE 212 212 /note="Tele-hemiaminal-histidine intermediate" H
BINDING 50 50 /ligand="dihydroxyacetone"
/ligand_id="ChEBI:CHEBI:16016"		 H
BINDING 103 103 /ligand="dihydroxyacetone"
/ligand_id="ChEBI:CHEBI:16016"		 D

Additional information [?]

Size range 310-395 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]