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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00824


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00824
General rule information [?]

Accession PRU00824
Dates 20-JUL-2010 (Created)
21-NOV-2019 (Last updated, Version 4)
Data class Domain;
Predictors PROSITE; PS51491; TAU_MAP_2
Name Tau and MAP proteins tubulin-binding repeat
Function The C-terminal region of a subset of Microtubule Associated Proteins (MAPs) contain three or four tandem repeats of a conserved domain of about thirty amino acid residues which is implicated in tubulin- binding and which seems to have a stiffening effect on microtubules.
Scope(s) Eukaryota
Eutheria
Example(s) Q5S6V2;

Propagated annotation [?]

Keywords [?]

Microtubule
Repeat

Gene Ontology [?]

GO:0005874; Cellular component:microtubule
GO:0007026; Biological process:negative regulation of microtubule depolymerization

Cross-references [?]

PROSITE PS00229; TAU_MAP_1; 1;

Features [?]

From: PS51491
Key From To Description Tag Condition FTGroup
REPEAT from to /note="Tau/MAP #"

Additional information [?]

Size range 21-42 amino acids
Related rules None
Fusion None
Repeats 3-4
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]