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annotation rule: PRU00824

General rule information [?]

Accession PRU00824
Dates 20-JUL-2010 (Created)
16-DEC-2016 (Last updated, Version 2)
Data class Domain
Predictors PROSITE; PS51491; TAU_MAP_2
Name Tau and MAP proteins tubulin-binding repeat
Function The C-terminal region of a subset of Microtubule Associated Proteins (MAPs) contain three or four tandem repeats of a conserved domain of about thirty amino acid residues which is implicated in tubulin- binding and which seems to have a stiffening effect on microtubules.

Propagated annotation [?]


Cross-references [?]

PROSITE PS00229; TAU_MAP_1; 1;

Gene Ontology [?]

GO:0005874; Cellular component: microtubule.
GO:0007026; Biological process: negative regulation of microtubule depolymerization.

Keywords [?]


Features [?]

From: PS51491
Key     From     To       Description   Tag   Condition   FTGroup
REPEAT     from     to       Tau/MAP #        

Additional information [?]

Size range 21-42 amino acids
Related rules None
Repeats 3-4
Topology Undefined
Example Q5S6V2 (TAU_PONPY)
Scope
Eukaryota; Eutheria
Comments None

Copyright

PROSITE is copyright. It is produced by the SIB Swiss Institute Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified. Usage by and for commercial entities requires a license agreement. For information about the licensing scheme send an email to license@isb-sib.ch or see: prosite_license.html.



UniProtKB rule member sequences [?]