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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00825


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00825
General rule information [?]

Accession PRU00825
Dates 18-NOV-2014 (Created)
21-NOV-2019 (Last updated, Version 4)
Data class Domain;
Predictors PROSITE; PS51492; PEPTIDASE_C23
Name Peptidase family C23 domain
Function The peptidase family C23 domain is a papain-like proteinase domain with catalytic cysteine and histidine residues.
Scope(s) Viruses
Betaflexiviridae
Example(s) Q64962;

Propagated annotation [?]

Keywords [?]

Hydrolase
Protease
Thiol protease
end case

Gene Ontology [?]

case <FTGroup:1>
GO:0004197; Molecular function:cysteine-type endopeptidase activity
GO:0016787; Molecular function:hydrolase activity
GO:0008233; Molecular function:peptidase activity

Features [?]

From: PS51492
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Peptidase C23 #"
ACT_SITE 5 5 C 1
ACT_SITE 86 86 H 1

Additional information [?]

Size range 80-101 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]