We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU00832
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00832
General rule information
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| Accession | PRU00832 |
| Dates | 08-DEC-2010 (Created)
21-NOV-2019 (Last updated, Version 4) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51499; APO |
Name | APO domain |
| Function | All members of the APO gene family contain an ~100 amino acid residue-spanning region (APO motif 1) with conserved Cys, His, Gly, and acidic and basic amino acids. This highly conserved APO1 motif is duplicated at the C terminus (designated APO motif 2). The conserved Cys in both motifs could provide ligands for tetranuclear Fe-S centers. |
| Scope(s) |
Eukaryota Arabidopsis |
| Example(s) | Q9FH50; |
Propagated annotation
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Comments
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| SIMILARITY | Belongs to the APO family. |
Features
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| From: PS51499 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="APO #" | |||||||||
Additional information
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| Size range | 76-97 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 2 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [4] All [ 4 ]
- Retrieve set of proteins with 3D structure for this domain