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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00836


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00836
General rule information [?]

Accession PRU00836
Dates 07-DEC-2010 (Created)
30-SEP-2022 (Last updated, Version 9)
Data class Domain;
Predictors PROSITE; PS51503; HIG1
Name HIG1 domain
Function HIG1 is a member of a well conserved eukaryote protein family. The predicted transmembrane helice (TMH) and loop regions represent the most highly conserved regions in these proteins.
Scope(s) Eukaryota
Example(s) Q6CWT4;

Propagated annotation [?]

Comments [?]

SUBCELLULAR LOCATIONMitochondrion membrane; Multi-pass membrane protein.

Keywords [?]

Mitochondrion

Gene Ontology [?]

GO:0031966; Cellular component:mitochondrial membrane

Cross-references [?]

General Transmembrane; -; 2;

Features [?]

From: PS51503
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="HIG1 #"

Additional information [?]

Size range 63-134 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]