ProRule PRU00851

General rule information [?]

Accession PRU00851
Dates 22-DEC-2011 (Created)
27-JUN-2022 (Last updated, Version 9)
Data class Domain;
Predictors PROSITE; PS51518; SGF29_C
Name SGF29 C-terminal domain
Function The SGF29 C-terminal domain contains a double Tudor-like motif that binds the H3K4me2/3 lysine methylation site on the N terminus of histone H3.
Scope(s) Eukaryota
Example(s) Q96ES7 (SGF29_HUMAN);

Propagated annotation [?]

Comments [?]

DOMAINThe SGF29 tudor-like domain mediates binding to methylated 'Lys-4' of histone H3 (H3K4me).
SIMILARITYBelongs to the SGF29 family.

Keywords [?]

Gene Ontology [?]

GO:0006325; Biological process:chromatin organization
GO:0006355; Biological process:regulation of DNA-templated transcription
GO:0006351; Biological process:DNA-templated transcription

Features [?]

From: PS51518
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="SGF29 C-terminal #"
REGION 44 46 /note="Histone H3K4me3 N-terminus binding" D-x*-[DE] 1
case <FTGroup:1>
REGION 91 94 /note="Histone H3K4me3 N-terminus binding"
end case
REGION 115 118 /note="Histone H3K4me3 binding" F-x* 1
SITE 89 89 /note="Histone H3K4me3 binding" Y 1
SITE 96 96 /note="Histone H3K4me3 binding" Y 1

Additional information [?]

Size range 126-152 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

View rule in raw text format (no links)

UniProtKB rule member sequences [?]