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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00853


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00853
General rule information [?]

Accession PRU00853
Dates 23-MAR-2011 (Created)
21-NOV-2019 (Last updated, Version 7)
Data class Domain;
Predictors PROSITE; PS51520; NSP2PRO
Name Alphavirus nsp2 protease (nsp2pro) domain
Function The nsp2pro domain is a member of peptidase family C9 of clan CA.
Scope(s) Viruses
Togaviridae
Example(s) Q4QXJ8;

Propagated annotation [?]

Keywords [?]

Protease

Features [?]

From: PS51520
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Peptidase C9 #"
ACT_SITE 10 10 /note="For cysteine protease nsP2 activity" C
ACT_SITE 80 80 /note="For cysteine protease nsP2 activity" H

Additional information [?]

Size range 310-369 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]