ProRule PRU00854
General rule information
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| PURL | https://purl.expasy.org/prosite/rule/PRU00854 |
| Accession | PRU00854 |
| Dates | 7-FEB-2011 (Created)
21-NOV-2019 (Last updated, Version 5) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51521; HTUSP |
Name | Herpesvirus tegument ubiquitin-specific protease (htUSP) domain |
| Function | All herpesviruses contain a Ubiquitin (Ub)-specific cysteine protease (USP) domain embedded within their large tegument protein. |
| Scope(s) |
Viruses Herpesviridae |
| Example(s) | P52340 (LTP_HHV6U); |
Propagated annotation
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Comments
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| SIMILARITY | Belongs to the herpesviridae large tegument protein family. |
Keywords
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Gene Ontology
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| GO:0019033; Cellular component:viral tegument |
Features
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| From: PS51521 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="Peptidase C76 #" | |||||||||
| case <FTGroup:1> | ||||||||||||
| SITE | 8 | 8 | /note="Important for catalytic activity" | Q | ||||||||
| end case | ||||||||||||
| ACT_SITE | 21 | 21 | C | 1 | ||||||||
| ACT_SITE | 156 | 156 | D | 1 | ||||||||
| ACT_SITE | 158 | 158 | H | 1 | ||||||||
Additional information
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| Size range | 203-236 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Viruses [23] All [ 23 ]
- Retrieve set of proteins with 3D structure for this domain