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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00854


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00854
General rule information [?]

Accession PRU00854
Dates 07-FEB-2011 (Created)
21-NOV-2019 (Last updated, Version 6)
Data class Domain;
Predictors PROSITE; PS51521; HTUSP
Name Herpesvirus tegument ubiquitin-specific protease (htUSP) domain
Function All herpesviruses contain a Ubiquitin (Ub)-specific cysteine protease (USP) domain embedded within their large tegument protein.
Scope(s) Viruses
Herpesviridae
Example(s) P52340;

Propagated annotation [?]

Comments [?]

SIMILARITYBelongs to the herpesviridae large tegument protein family.

Keywords [?]

Virion
Virion tegument

Gene Ontology [?]

GO:0019033; Cellular component:viral tegument

Features [?]

From: PS51521
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Peptidase C76 #"
case <FTGroup:1>
SITE 8 8 /note="Important for catalytic activity" Q
end case
ACT_SITE 21 21 C 1
ACT_SITE 156 156 D 1
ACT_SITE 158 158 H 1

Additional information [?]

Size range 203-236 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]