ProRule PRU00858

General rule information [?]

Accession PRU00858
Dates 4-AUG-2011 (Created)
27-JUN-2022 (Last updated, Version 7)
Data class Domain;
Predictors PROSITE; PS51526; RFX_DBD
Name RFX-type winged-helix DNA-binding domain
Function The characteristic RFX-type HTH DNA binding domain has been recruited into otherwise very divergent regulatory factors functioning in a diverse spectrum of unrelated systems, including regulation of the mitotic cell cycle in fission yeast, the control of the immune response in mammals, and infection by human hepatitis B virus.
Scope(s) Eukaryota
Example(s) P48379 (RFX2_MOUSE);

Propagated annotation [?]

Comments [?]

SIMILARITYBelongs to the RFX family.

Keywords [?]

Gene Ontology [?]

GO:0003677; Molecular function:DNA binding
GO:0005634; Cellular component:nucleus
GO:0006351; Biological process:DNA-templated transcription
GO:0006355; Biological process:regulation of DNA-templated transcription

Features [?]

From: PS51526
Key From To Description Tag Condition FTGroup
DNA_BIND from to /note="RFX-type winged-helix #"

Additional information [?]

Size range 65-90 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

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UniProtKB rule member sequences [?]