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annotation rule: PRU00858

General rule information [?]

Accession PRU00858
Dates 4-AUG-2011 (Created)
21-NOV-2019 (Last updated, Version 6)
Data class Domain
Predictors PROSITE; PS51526; RFX_DBD
Name RFX-type winged-helix DNA-binding domain
Function The characteristic RFX-type HTH DNA binding domain has been recruited into otherwise very divergent regulatory factors functioning in a diverse spectrum of unrelated systems, including regulation of the mitotic cell cycle in fission yeast, the control of the immune response in mammals, and infection by human hepatitis B virus.

Propagated annotation [?]

Comments [?]

Subcellular location Nucleus.
Similarity Belongs to the RFX family.

Gene Ontology [?]

GO:0003677; Molecular function: DNA binding.
GO:0005634; Cellular component: nucleus.
GO:0006351; Biological process: transcription, DNA-templated.
GO:0006355; Biological process: regulation of transcription, DNA-templated.

Keywords [?]

Features [?]

From: PS51526
Key     From     To       Description   Tag   Condition   FTGroup
DNA_BIND     from     to       RFX-type winged-helix #        

Additional information [?]

Size range 65-90 amino acids
Related rules None
Repeats 1
Topology Undefined
Example P48379 (RFX2_MOUSE)
Comments None


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UniProtKB rule member sequences [?]