ProRule PRU00858
General rule information
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| Accession | PRU00858 |
| Dates | 4-AUG-2011 (Created)
27-JUN-2022 (Last updated, Version 7) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51526; RFX_DBD |
Name | RFX-type winged-helix DNA-binding domain |
| Function | The characteristic RFX-type HTH DNA binding domain has been recruited into otherwise very divergent regulatory factors functioning in a diverse spectrum of unrelated systems, including regulation of the mitotic cell cycle in fission yeast, the control of the immune response in mammals, and infection by human hepatitis B virus. |
| Scope(s) |
Eukaryota |
| Example(s) | P48379 (RFX2_MOUSE); |
Propagated annotation
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Comments
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| SUBCELLULAR LOCATION | Nucleus. |
| SIMILARITY | Belongs to the RFX family. |
Keywords
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Gene Ontology
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| GO:0003677; Molecular function:DNA binding |
| GO:0005634; Cellular component:nucleus |
| GO:0006351; Biological process:DNA-templated transcription |
| GO:0006355; Biological process:regulation of DNA-templated transcription |
Features
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| From: PS51526 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DNA_BIND | from | to | /note="RFX-type winged-helix #" | |||||||||
Additional information
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| Size range | 65-90 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [41] All [ 41 ]
- Retrieve set of proteins with 3D structure for this domain