PRU00868

General rule information [?]

Accession	PRU00868
Dates	3-AUG-2011 (Created) 21-NOV-2019 (Last updated, Version 4)

Data class

Domain

Predictors

PROSITE; PS51535; PESTIVIRUS_NS3PRO

Name	Pestivirus NS3 protease (NS3pro) domain

Function

The NS3 protease (NS3pro) domain is of some 180 aa with a catalytic triad of His-Asp-Ser.

Propagated annotation [?]

Gene Ontology [?]

case <FTGroup:1>

GO:0016787; Molecular function: hydrolase activity.
GO:0008233; Molecular function: peptidase activity.
GO:0008236; Molecular function: serine-type peptidase activity.

Keywords [?]

Hydrolase
Protease
Serine protease

end case

Features [?]

From: PS51535

Key From To Description Tag Condition FTGroup

DOMAIN from to Peptidase S31 #

ACT_SITE 69 69 Charge relay system; for serine protease NS3 activity H 1

ACT_SITE 106 106 Charge relay system; for serine protease NS3 activity D 1

ACT_SITE 163 163 Charge relay system; for serine protease NS3 activity S 1

Additional information [?]

Size range	164-184 amino acids
Related rules	None
Repeats	1
Topology	Undefined
Example	P19711 (POLG_BVDVN)
Scope	Viruses; Pestivirus
Comments	None

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

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UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets

Viruses [5]
Retrieve set of proteins with 3D structure for this domain