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ProRule PRU00868


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PURL: https://purl.expasy.org/prosite/rule/PRU00868
General rule information [?]

Accession PRU00868
Dates 03-AUG-2011 (Created)
21-NOV-2019 (Last updated, Version 5)
Data class Domain;
Predictors PROSITE; PS51535; PESTIVIRUS_NS3PRO
Name Pestivirus NS3 protease (NS3pro) domain
Function The NS3 protease (NS3pro) domain is of some 180 aa with a catalytic triad of His-Asp-Ser.
Scope(s) Viruses
Pestivirus
Example(s) P19711 (POLG_BVDVN);

Propagated annotation [?]

Keywords [?]

Hydrolase
Protease
Serine protease
end case

Gene Ontology [?]

case <FTGroup:1>
GO:0016787; Molecular function:hydrolase activity
GO:0008233; Molecular function:peptidase activity
GO:0008236; Molecular function:serine-type peptidase activity

Features [?]

From: PS51535
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Peptidase S31 #"
ACT_SITE 69 69 /note="Charge relay system; for serine protease NS3 activity" H 1
ACT_SITE 106 106 /note="Charge relay system; for serine protease NS3 activity" D 1
ACT_SITE 163 163 /note="Charge relay system; for serine protease NS3 activity" S 1

Additional information [?]

Size range 164-184 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

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UniProtKB rule member sequences [?]