ProRule PRU00868
General rule information
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| Accession | PRU00868 |
| Dates | 3-AUG-2011 (Created)
21-NOV-2019 (Last updated, Version 4) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51535; PESTIVIRUS_NS3PRO |
Name | Pestivirus NS3 protease (NS3pro) domain |
| Function | The NS3 protease (NS3pro) domain is of some 180 aa with a catalytic triad of His-Asp-Ser. |
| Scope(s) |
Viruses Pestivirus |
| Example(s) | P19711 (POLG_BVDVN); |
Propagated annotation
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Keywords
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| Hydrolase | |
| Protease | |
| Serine protease | |
| end case | |
Gene Ontology
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| case <FTGroup:1> | |
| GO:0016787; Molecular function:hydrolase activity | |
| GO:0008233; Molecular function:peptidase activity | |
| GO:0008236; Molecular function:serine-type peptidase activity | |
Features
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| From: PS51535 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="Peptidase S31 #" | |||||||||
| ACT_SITE | 69 | 69 | /note="Charge relay system; for serine protease NS3 activity" | H | 1 | |||||||
| ACT_SITE | 106 | 106 | /note="Charge relay system; for serine protease NS3 activity" | D | 1 | |||||||
| ACT_SITE | 163 | 163 | /note="Charge relay system; for serine protease NS3 activity" | S | 1 | |||||||
Additional information
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| Size range | 164-184 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Viruses [5] All [ 5 ]
- Retrieve set of proteins with 3D structure for this domain