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annotation rule: PRU00868

General rule information [?]

Accession PRU00868
Dates 3-AUG-2011 (Created)
21-NOV-2019 (Last updated, Version 4)
Data class Domain
Predictors PROSITE; PS51535; PESTIVIRUS_NS3PRO
Name Pestivirus NS3 protease (NS3pro) domain
Function The NS3 protease (NS3pro) domain is of some 180 aa with a catalytic triad of His-Asp-Ser.

Propagated annotation [?]


Gene Ontology [?]

case <FTGroup:1>
GO:0016787; Molecular function: hydrolase activity.
GO:0008233; Molecular function: peptidase activity.
GO:0008236; Molecular function: serine-type peptidase activity.

Keywords [?]

Hydrolase
Protease
Serine protease
end case


Features [?]

From: PS51535
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       Peptidase S31 #        
ACT_SITE     69     69       Charge relay system; for serine protease NS3 activity     H   1
ACT_SITE     106     106       Charge relay system; for serine protease NS3 activity     D   1
ACT_SITE     163     163       Charge relay system; for serine protease NS3 activity     S   1

Additional information [?]

Size range 164-184 amino acids
Related rules None
Repeats 1
Topology Undefined
Example P19711 (POLG_BVDVN)
Scope
Viruses; Pestivirus
Comments None

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.


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UniProtKB rule member sequences [?]