We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU00880
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00880
General rule information
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| Accession | PRU00880 |
| Dates | 23-MAR-2012 (Created)
03-JAN-2020 (Last updated, Version 5) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51547; C2_PI3K |
Name | C2 phosphatidylinositol 3-kinase (PI3K)-type domain |
| Function | The putative membrane-binding PI3K-type C2 domain is an eight- stranded antiparallel beta-sandwich consisting of two four-stranded beta- sheets. |
| Scope(s) |
Eukaryota |
| Example(s) | P42339; |
Propagated annotation
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Comments
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| SIMILARITY | Belongs to the PI3/PI4-kinase family. |
Features
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| From: PS51547 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="C2 PI3K-type #" | |||||||||
Additional information
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| Size range | 801-1857 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [40] All [ 40 ]
- Retrieve set of proteins with 3D structure for this domain