General rule information
[?]
Accession |
PRU00881 |
Dates |
23-MAR-2012 (Created) 21-NOV-2019 (Last updated, Version 4) |
Predictors |
PROSITE; PS51548; BIRNAVIRUS_VP4_PRO
|
Name |
Birnavirus VP4 protease domain |
Function |
The birnavirus VP4 protease domain displays a catalytic serine/ lysine dyad in its active site. |
Propagated annotation
[?]
case <FTGroup:1>
Function |
Protease VP4 is a serine protease that cleaves the polyprotein into its final products. Pre-VP2 is first partially cleaved, and may be completely processed by VP4 upon capsid maturation. |
end case
case <FTGroup:1>
GO:0016787; Molecular function: hydrolase activity.
GO:0008233; Molecular function: peptidase activity.
GO:0008236; Molecular function: serine-type peptidase activity.
end case
From: PS51548 |
Key
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From
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To
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Description
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Tag
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Condition
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|
FTGroup
|
DOMAIN
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from
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to
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Peptidase S50 #
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|
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ACT_SITE
|
|
125
|
|
125
|
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Nucleophile
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|
|
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S
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1
|
ACT_SITE
|
|
163
|
|
163
|
|
|
|
|
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K
|
|
1
|
Additional information
[?]
Size range |
972-1069 amino acids |
Related rules |
None |
Repeats |
1 |
Topology |
Undefined |
Example |
P22351 (POLS_IBDVS) |
Scope |
Viruses; Birnaviridae |
Comments |
None |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and
distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives
(CC BY-NC-ND 4.0) License, see
prosite_license.html.
UniProtKB rule member sequences
[?]