ProRule PRU00881

General rule information [?]

Accession PRU00881
Dates 23-MAR-2012 (Created)
21-NOV-2019 (Last updated, Version 4)
Data class Domain;
Name Birnavirus VP4 protease domain
Function The birnavirus VP4 protease domain displays a catalytic serine/ lysine dyad in its active site.
Scope(s) Viruses
Example(s) P22351 (POLS_IBDVS);

Propagated annotation [?]

Comments [?]

case <FTGroup:1>
FUNCTIONProtease VP4 is a serine protease that cleaves the polyprotein into its final products. Pre-VP2 is first partially cleaved, and may be completely processed by VP4 upon capsid maturation.
end case

Keywords [?]

Gene Ontology [?]

case <FTGroup:1>
GO:0016787; Molecular function:hydrolase activity
GO:0008233; Molecular function:peptidase activity
GO:0008236; Molecular function:serine-type peptidase activity

Features [?]

From: PS51548
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Peptidase S50 #"
ACT_SITE 125 125 /note="Nucleophile" S 1
ACT_SITE 163 163 K 1

Additional information [?]

Size range 972-1069 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


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UniProtKB rule member sequences [?]