ProRule PRU00881
General rule information
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Accession | PRU00881 |
Dates | 23-MAR-2012 (Created)
21-NOV-2019 (Last updated, Version 4) |
Data class | Domain; |
Predictors |
PROSITE; PS51548; BIRNAVIRUS_VP4_PRO |
Name | Birnavirus VP4 protease domain |
Function | The birnavirus VP4 protease domain displays a catalytic serine/ lysine dyad in its active site. |
Scope(s) |
Viruses Birnaviridae |
Example(s) | P22351 (POLS_IBDVS); |
Propagated annotation
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Comments
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case <FTGroup:1> | |
FUNCTION | Protease VP4 is a serine protease that cleaves the polyprotein into its final products. Pre-VP2 is first partially cleaved, and may be completely processed by VP4 upon capsid maturation. |
end case |
Keywords
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Hydrolase | |
Protease | |
Serine protease | |
end case |
Gene Ontology
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case <FTGroup:1> | |
GO:0016787; Molecular function:hydrolase activity | |
GO:0008233; Molecular function:peptidase activity | |
GO:0008236; Molecular function:serine-type peptidase activity |
Features
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From: PS51548 | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
DOMAIN | from | to | /note="Peptidase S50 #" | |||||||||
ACT_SITE | 125 | 125 | /note="Nucleophile" | S | 1 | |||||||
ACT_SITE | 163 | 163 | K | 1 |
Additional information
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Size range | 972-1069 amino acids |
Related rules |
None |
Fusion | None |
Repeats | 1 |
Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Viruses [15] All [ 15 ]
- Retrieve set of proteins with 3D structure for this domain