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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00889


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00889
General rule information [?]

Accession PRU00889
Dates 25-NOV-2011 (Created)
21-NOV-2019 (Last updated, Version 9)
Data class Domain;
Predictors
case c? <Length>=200> and <Length<=412>
PROSITE; PS51556; SAM_MT_MG_PIX
end case
Name Magnesium protoporphyrin IX methyltransferase (EC 2.1.1.11)
Function Magnesium protoporphyrin IX methyltransferase (EC 2.1.1.11) is an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to magnesium protoporphyrin IX to form magnesium protoporphyrin IX 13-methyl ester and S-adenosyl-L-homocysteine.
Scope(s) Bacteria
Example(s) P26236;

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name + RecName: EC=2.1.1.11;

Comments [?]

CATALYTIC ACTIVITY Reaction=Mg-protoporphyrin IX + S-adenosyl-L-methionine = Mg- protoporphyrin IX 13-monomethyl ester + S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:17809, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:60491, ChEBI:CHEBI:60492; EC=2.1.1.11;
SIMILARITYBelongs to the class I-like SAM-binding methyltransferase superfamily. Magnesium protoporphyrin O-methyltransferase family.

Keywords [?]

Chlorophyll biosynthesis
Methyltransferase
Photosynthesis
S-adenosyl-L-methionine
Transferase

Gene Ontology [?]

GO:0046406; Molecular function:magnesium protoporphyrin IX methyltransferase activity
GO:0015979; Biological process:photosynthesis
GO:0030494; Biological process:bacteriochlorophyll biosynthetic process
GO:0032259; Biological process:methylation
GO:0046500; Biological process:S-adenosylmethionine metabolic process

Features [?]


Additional information [?]

Size range unlimited amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]