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ProRule PRU00893


General rule information [?]

Accession PRU00893
Dates 25-NOV-2011 (Created)
21-NOV-2019 (Last updated, Version 9)
Data class Domain;
Predictors
case c? <Length>=229> and <Length<=343>
PROSITE; PS51560; SAM_MT_NNT1
end case
Name Nicotinamide N-methyltransferase (EC 2.1.1.1)
Function Nicotinamide N-methyltransferase (EC 2.1.1.1) is an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to nicotinamide to form 1-methylnicotinamide and S-adenosyl-L-homocysteine.
Scope(s) Eukaryota
Dikarya
Example(s) Q9UT28 (EFM7_SCHPO);

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name + RecName: EC=2.1.1.1;

Comments [?]

CATALYTIC ACTIVITY Reaction=nicotinamide + S-adenosyl-L-methionine = 1-methylnicotinamide + S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:23884, ChEBI:CHEBI:16797, ChEBI:CHEBI:17154, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789; EC=2.1.1.1;
SIMILARITYBelongs to the class I-like SAM-binding methyltransferase superfamily. NNT1 family.

Keywords [?]


Gene Ontology [?]

GO:0008112; Molecular function:nicotinamide N-methyltransferase activity
GO:0032259; Biological process:methylation
GO:0046500; Biological process:S-adenosylmethionine metabolic process

Features [?]


Additional information [?]

Size range unlimited amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

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UniProtKB rule member sequences [?]