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annotation rule: PRU00893

General rule information [?]

Accession PRU00893
Dates 25-NOV-2011 (Created)
21-NOV-2019 (Last updated, Version 9)
Data class Domain
case <Length>=229> and <Length<=343>
Predictors PROSITE; PS51560; SAM_MT_NNT1
end case

Name Nicotinamide N-methyltransferase (EC 2.1.1.1)
Function Nicotinamide N-methyltransferase (EC 2.1.1.1) is an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to nicotinamide to form 1-methylnicotinamide and S-adenosyl-L-homocysteine.

Propagated annotation [?]


Description [?]

+ RecName: EC 2.1.1.1;

Comments [?]

Catalytic activity RHEA:23884: nicotinamide + S-adenosyl-L-methionine = 1-methylnicotinamide + S-adenosyl-L-homocysteine
EC 2.1.1.1
Similarity Belongs to the class I-like SAM-binding methyltransferase superfamily. NNT1 family.

Gene Ontology [?]

GO:0008112; Molecular function: nicotinamide N-methyltransferase activity.
GO:0032259; Biological process: methylation.
GO:0046500; Biological process: S-adenosylmethionine metabolic process.

Keywords [?]


Additional information [?]

Size range unlimited amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q9UT28 (EFM7_SCHPO)
Scope
Eukaryota; Dikarya
Comments None

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets
Eukaryota [14]