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| annotation rule: PRU00893 |
General rule information
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| Accession | PRU00893 |
| Dates | 25-NOV-2011 (Created) 21-NOV-2019 (Last updated, Version 9) |
| Data class | Domain |
case <Length>=229> and <Length<=343>
| Predictors | PROSITE; PS51560; SAM_MT_NNT1 |
end case
| Name | Nicotinamide N-methyltransferase (EC 2.1.1.1) |
| Function | Nicotinamide N-methyltransferase (EC 2.1.1.1) is an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to nicotinamide to form 1-methylnicotinamide and S-adenosyl-L-homocysteine. |
Propagated annotation
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Description
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| + RecName: EC 2.1.1.1; |
Comments
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| Catalytic activity | RHEA:23884: nicotinamide + S-adenosyl-L-methionine = 1-methylnicotinamide + S-adenosyl-L-homocysteine
EC 2.1.1.1 |
| Similarity | Belongs to the class I-like SAM-binding methyltransferase superfamily. NNT1 family. |
Gene Ontology
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GO:0008112; Molecular function: nicotinamide N-methyltransferase activity.
GO:0032259; Biological process: methylation.
GO:0046500; Biological process: S-adenosylmethionine metabolic process.
GO:0032259; Biological process: methylation.
GO:0046500; Biological process: S-adenosylmethionine metabolic process.
Keywords
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Additional information
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| Size range | unlimited amino acids |
| Related rules | None |
| Repeats | 1 |
| Topology | Undefined |
| Example | Q9UT28 (EFM7_SCHPO) |
| Scope | Eukaryota; Dikarya |
| Comments | None |
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UniProtKB rule member sequences
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