General rule information
21-NOV-2019 (Last updated, Version 9)
||PROSITE; PS51570; SAM_MT43_SUVAR420_2
||Histone-lysine N-methyltransferase (EC 126.96.36.199) |
|| Histone-lysine N-methyltransferase (EC 188.8.131.52) is an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to L-lysine- [histone] to form N(6)-methyl-L-lysine-[histone] and S-adenosyl-L- homocysteine. |
||RHEA:10024: L-lysyl-[histone] + S-adenosyl-L-methionine = H(+) + N(6)-methyl-L-lysyl-[histone] + S-adenosyl-L-homocysteine
||Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar4-20 subfamily.
; Molecular function: histone methyltransferase activity (H4-K20 specific).
; Biological process: histone H4-K20 trimethylation.
||unlimited amino acids
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UniProtKB rule member sequences