ProRule PRU00922
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PURL: https://purl.expasy.org/prosite/rule/PRU00922
General rule information
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| Accession | PRU00922 |
| Dates | 25-NOV-2011 (Created)
11-JAN-2024 (Last updated, Version 17) |
| Data class | Domain; |
| Predictors |
case c? <Length>=756> and <Length<=1134>
PROSITE; PS51589; SAM_MT56_VP3 end case
|
Name | Viral protein 3 containing mRNA (guanine-N(7))-methyltransferase. |
| Function | mRNA (guanine-N(7))-methyltransferase (EC 2.1.1.56) is an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to G(5')pppR-RNA to form m(7)G(5')pppR-RNA and S-adenosyl-L-homocysteine. |
| Scope(s) |
Viruses |
| Example(s) | Q65526; |
Propagated annotation
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Identifier, protein and gene names
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| Protein name | + RecName: EC=2.1.1.56; |
Comments
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| CATALYTIC ACTIVITY | Reaction=a 5'-end (5'-triphosphoguanosine)-ribonucleoside in mRNA + S- adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'- triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L- homocysteine; Xref=Rhea:RHEA:67008, Rhea:RHEA-COMP:17166, Rhea:RHEA- COMP:17167, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:156461, ChEBI:CHEBI:167617; EC=2.1.1.56; |
Keywords
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Gene Ontology
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| GO:0004482; Molecular function:mRNA 5'-cap (guanine-N7-)-methyltransferase activity |
| GO:0032259; Biological process:methylation |
| GO:0046500; Biological process:S-adenosylmethionine metabolic process |
Features
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Additional information
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| Size range | unlimited amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
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UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Viruses [28] All [ 28 ]
- Retrieve set of proteins with 3D structure for this domain