PRU00922

General rule information [?]

Accession	PRU00922
Dates	25-NOV-2011 (Created) 12-MAR-2021 (Last updated, Version 14)

Data class

Domain

case <Length>=756> and <Length<=1134>

Predictors

PROSITE; PS51589; SAM_MT56_VP3

end case

Name	Viral protein 3 containing mRNA (guanine-N(7))-methyltransferase.

Function

mRNA (guanine-N(7))-methyltransferase (EC 2.1.1.56) is an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to G(5')pppR-RNA to form m(7)G(5')pppR-RNA and S-adenosyl-L-homocysteine.

Propagated annotation [?]

Description [?]

+ RecName: EC 2.1.1.56;

Comments [?]

Catalytic activity

RHEA:67008: a 5'-end (5'-triphosphoguanosine)-(ribonucleoside) in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-homocysteine
EC 2.1.1.56

Gene Ontology [?]

GO:0004482; Molecular function: mRNA (guanine-N7-)-methyltransferase activity.
GO:0032259; Biological process: methylation.
GO:0046500; Biological process: S-adenosylmethionine metabolic process.

Keywords [?]

Methyltransferase
S-adenosyl-L-methionine
Transferase

Additional information [?]

Size range	unlimited amino acids
Related rules	None
Repeats	1
Topology	Undefined
Example	Q65526 (VP3_ROTBS)
Scope	Viruses
Comments	None

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

View rule in raw text format (no links)

UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets

Viruses [28]
Retrieve set of proteins with 3D structure for this domain