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annotation rule: PRU00930

General rule information [?]

Accession PRU00930
Dates 14-DEC-2011 (Created)
21-NOV-2019 (Last updated, Version 7)
Data class Domain
case <Length>=725> and <Length<=1087>
Predictors PROSITE; PS51598; SAM_CHO2
end case

Name Phosphatidylethanolamine N-methyltransferase
Function Phosphatidylethanolamine N-methyltransferase (EC is an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to phosphatidylethanolamine to form phosphatidyl-N-methylethanolamine and S- adenosyl-L-homocysteine.

Propagated annotation [?]

Description [?]

+ RecName: EC;

Comments [?]

Catalytic activity RHEA:11164: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + S-adenosyl-L-methionine = 1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine + H(+) + S-adenosyl-L-homocysteine
Similarity Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.

Gene Ontology [?]

GO:0004608; Molecular function: phosphatidylethanolamine N-methyltransferase activity.
GO:0008654; Biological process: phospholipid biosynthetic process.
GO:0032259; Biological process: methylation.
GO:0046500; Biological process: S-adenosylmethionine metabolic process.

Keywords [?]

Additional information [?]

Size range unlimited amino acids
Related rules None
Repeats 1
Topology Undefined
Example A2R616 (CHO2_ASPNC)
Eukaryota; Dikarya
Comments None


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UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets
Eukaryota [61]