ProRule PRU00930

General rule information [?]

Accession PRU00930
Dates 14-DEC-2011 (Created)
21-NOV-2019 (Last updated, Version 7)
Data class Domain;
case c? <Length>=725> and <Length<=1087>
end case
Name Phosphatidylethanolamine N-methyltransferase
Function Phosphatidylethanolamine N-methyltransferase (EC is an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to phosphatidylethanolamine to form phosphatidyl-N-methylethanolamine and S- adenosyl-L-homocysteine.
Scope(s) Eukaryota
Example(s) A2R616 (CHO2_ASPNC);

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name + RecName: EC=;

Comments [?]

CATALYTIC ACTIVITY Reaction=a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + S-adenosyl-L- methionine = 1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine + H(+) + S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:11164, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:64573, ChEBI:CHEBI:64612; EC=;
SIMILARITYBelongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.

Keywords [?]

Gene Ontology [?]

GO:0004608; Molecular function:phosphatidylethanolamine N-methyltransferase activity
GO:0008654; Biological process:phospholipid biosynthetic process
GO:0032259; Biological process:methylation
GO:0046500; Biological process:S-adenosylmethionine metabolic process

Features [?]

Additional information [?]

Size range unlimited amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


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UniProtKB rule member sequences [?]