General rule information
[?]
Accession |
PRU00930 |
Dates |
14-DEC-2011 (Created) 21-NOV-2019 (Last updated, Version 7) |
case <Length>=725> and <Length<=1087>
Predictors |
PROSITE; PS51598; SAM_CHO2
|
end case
Name |
Phosphatidylethanolamine N-methyltransferase |
Function |
Phosphatidylethanolamine N-methyltransferase (EC 2.1.1.17) is an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to phosphatidylethanolamine to form phosphatidyl-N-methylethanolamine and S- adenosyl-L-homocysteine. |
Propagated annotation
[?]
Catalytic activity |
RHEA:11164: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + S-adenosyl-L-methionine = 1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine + H(+) + S-adenosyl-L-homocysteine
EC 2.1.1.17
|
Similarity |
Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family. |
GO:0004608; Molecular function: phosphatidylethanolamine N-methyltransferase activity.
GO:0008654; Biological process: phospholipid biosynthetic process.
GO:0032259; Biological process: methylation.
GO:0046500; Biological process: S-adenosylmethionine metabolic process.
Additional information
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Size range |
unlimited amino acids |
Related rules |
None |
Repeats |
1 |
Topology |
Undefined |
Example |
A2R616 (CHO2_ASPNC) |
Scope |
Eukaryota; Dikarya |
Comments |
None |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and
distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives
(CC BY-NC-ND 4.0) License, see
prosite_license.html.
UniProtKB rule member sequences
[?]
UniProtKB/Swiss-Prot sets