PRU00942

General rule information [?]

Accession	PRU00942
Dates	14-DEC-2011 (Created) 21-NOV-2019 (Last updated, Version 6)

Data class

Domain

case <Length>=258> and <Length<=388>

Predictors

PROSITE; PS51610; SAM_CLNMT

end case

Name	Calmodulin-lysine N-methyltransferase

Function

Calmodulin-lysine N-methyltransferase (EC 2.1.1.60) is an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to calmodulin L-lysine to form calmodulin N(6)-methyl-L-lysine and S-adenosyl-L- homocysteine.

Propagated annotation [?]

Description [?]

+ RecName: EC 2.1.1.60;

Comments [?]

Catalytic activity	RHEA:21556: [calmodulin]-L-lysine + S-adenosyl-L-methionine = [calmodulin]-N(6)-methyl-L-lysine + H(+) + S-adenosyl-L-homocysteine EC 2.1.1.60
Similarity	Belongs to the class I-like SAM-binding methyltransferase superfamily. CLNMT methyltransferase family.

Gene Ontology [?]

GO:0018025; Molecular function: calmodulin-lysine N-methyltransferase activity.
GO:0032259; Biological process: methylation.
GO:0046500; Biological process: S-adenosylmethionine metabolic process.

Keywords [?]

Methyltransferase
S-adenosyl-L-methionine
Transferase

Additional information [?]

Size range	unlimited amino acids
Related rules	None
Repeats	1
Topology	Undefined
Example	Q7Z624 (CMKMT_HUMAN)
Scope	Eukaryota; Euteleostomi
Comments	None

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

View rule in raw text format (no links)

UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets

Eukaryota [5]
Retrieve set of proteins with 3D structure for this domain