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| annotation rule: PRU00942 |
General rule information
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| Accession | PRU00942 |
| Dates | 14-DEC-2011 (Created) 21-NOV-2019 (Last updated, Version 6) |
| Data class | Domain |
case <Length>=258> and <Length<=388>
| Predictors | PROSITE; PS51610; SAM_CLNMT |
end case
| Name | Calmodulin-lysine N-methyltransferase |
| Function | Calmodulin-lysine N-methyltransferase (EC 2.1.1.60) is an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to calmodulin L-lysine to form calmodulin N(6)-methyl-L-lysine and S-adenosyl-L- homocysteine. |
Propagated annotation
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Description
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| + RecName: EC 2.1.1.60; |
Comments
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| Catalytic activity | RHEA:21556: [calmodulin]-L-lysine + S-adenosyl-L-methionine = [calmodulin]-N(6)-methyl-L-lysine + H(+) + S-adenosyl-L-homocysteine
EC 2.1.1.60 |
| Similarity | Belongs to the class I-like SAM-binding methyltransferase superfamily. CLNMT methyltransferase family. |
Gene Ontology
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GO:0018025; Molecular function: calmodulin-lysine N-methyltransferase activity.
GO:0032259; Biological process: methylation.
GO:0046500; Biological process: S-adenosylmethionine metabolic process.
GO:0032259; Biological process: methylation.
GO:0046500; Biological process: S-adenosylmethionine metabolic process.
Keywords
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Additional information
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| Size range | unlimited amino acids |
| Related rules | None |
| Repeats | 1 |
| Topology | Undefined |
| Example | Q7Z624 (CMKMT_HUMAN) |
| Scope | Eukaryota; Euteleostomi |
| Comments | None |
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UniProtKB rule member sequences
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UniProtKB/Swiss-Prot sets
Eukaryota [5]
- Retrieve set of proteins with 3D structure for this domain