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annotation rule: PRU00942

General rule information [?]

Accession PRU00942
Dates 14-DEC-2011 (Created)
21-NOV-2019 (Last updated, Version 6)
Data class Domain
case <Length>=258> and <Length<=388>
Predictors PROSITE; PS51610; SAM_CLNMT
end case

Name Calmodulin-lysine N-methyltransferase
Function Calmodulin-lysine N-methyltransferase (EC 2.1.1.60) is an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to calmodulin L-lysine to form calmodulin N(6)-methyl-L-lysine and S-adenosyl-L- homocysteine.

Propagated annotation [?]


Description [?]

+ RecName: EC 2.1.1.60;

Comments [?]

Catalytic activity RHEA:21556: [calmodulin]-L-lysine + S-adenosyl-L-methionine = [calmodulin]-N(6)-methyl-L-lysine + H(+) + S-adenosyl-L-homocysteine
EC 2.1.1.60
Similarity Belongs to the class I-like SAM-binding methyltransferase superfamily. CLNMT methyltransferase family.

Gene Ontology [?]

GO:0018025; Molecular function: calmodulin-lysine N-methyltransferase activity.
GO:0032259; Biological process: methylation.
GO:0046500; Biological process: S-adenosylmethionine metabolic process.

Keywords [?]


Additional information [?]

Size range unlimited amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q7Z624 (CMKMT_HUMAN)
Scope
Eukaryota; Euteleostomi
Comments None

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



UniProtKB rule member sequences [?]