ProRule PRU00943
General rule information
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| Accession | PRU00943 |
| Dates | 14-DEC-2011 (Created)
3-SEP-2024 (Last updated, Version 9) |
| Data class | Domain; |
| Predictors |
case c? <Length>=400> and <Length<=600>
PROSITE; PS51611; SAM_MT59 end case
|
Name | [Cytochrome c]-lysine N-methyltransferase |
| Function | [Cytochrome c]-lysine N-methyltransferase (EC 2.1.1.59) is an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to [cytochrome c]-L-lysine to form [cytochrome c]-N(6)-methyl-L-lysine and S- adenosyl-L-homocysteine. |
| Scope(s) |
Eukaryota Saccharomycetaceae |
| Example(s) | Q6FR37 (CTM1_CANGA); |
Propagated annotation
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Identifier, protein and gene names
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| Protein name | + RecName: EC=2.1.1.59; |
Comments
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| CATALYTIC ACTIVITY | Reaction=L-lysyl-[cytochrome c] + S-adenosyl-L-methionine = N(6)- methyl-L-lysyl-[cytochrome c] + S-adenosyl-L-homocysteine + H(+); Xref=Rhea:RHEA:24312, Rhea:RHEA-COMP:9754, Rhea:RHEA-COMP:9755, ChEBI:CHEBI:15378, ChEBI:CHEBI:29969, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:61929; EC=2.1.1.59; |
| SIMILARITY | Belongs to the class V-like SAM-binding methyltransferase superfamily. |
Keywords
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Gene Ontology
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| GO:0000277; Molecular function:[cytochrome c]-lysine N-methyltransferase activity |
Features
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Additional information
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| Size range | unlimited amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
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UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [4] All [ 4 ]
- Retrieve set of proteins with 3D structure for this domain