ProRule PRU00946
General rule information
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| PURL | https://purl.expasy.org/prosite/rule/PRU00946 |
| Accession | PRU00946 |
| Dates | 14-DEC-2011 (Created)
19-NOV-2022 (Last updated, Version 10) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51614; SAM_MT_ADRIFT |
Name | Adrift-type ribose 2'-O-methyltransferase (EC 2.1.1.-) domain |
| Function | 2'-O-methyltransferase |
| Scope(s) |
Viruses Eukaryota Metazoa |
| Example(s) | Q5RAY7 (CMTR2_PONAB); |
Propagated annotation
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Identifier, protein and gene names
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| Protein name | + RecName: EC=2.1.1.-; |
Keywords
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Gene Ontology
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| GO:0008168; Molecular function:methyltransferase activity |
Features
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| From: PS51614 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="Adrift-type SAM-dependent 2'-O-MTase #" | |||||||||
| ACT_SITE | 168 | 168 | /note="Proton acceptor" | K | ||||||||
| BINDING | 40 | 40 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789" |
G | ||||||||
| BINDING | 59 | 59 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789" |
W | ||||||||
| BINDING | 128 | 128 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789" |
D | ||||||||
Additional information
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| Size range | 199-224 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [5] Viruses [6] All [ 11 ]
- Retrieve set of proteins with 3D structure for this domain