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annotation rule: PRU00947

General rule information [?]

Accession PRU00947
Dates 14-DEC-2011 (Created)
21-NOV-2019 (Last updated, Version 8)
Data class Domain
case <Length>=282> and <Length<=424>
end case

Name Putrescine N-methyltransferase
Function Putrescine N-methyltransferase (EC is an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to putrescine to form N-methylputrescine and S-adenosyl-L-homocysteine.

Propagated annotation [?]

Description [?]

+ RecName: EC;

Comments [?]

Catalytic activity RHEA:15037: putrescine + S-adenosyl-L-methionine = H(+) + N-methylputrescine + S-adenosyl-L-homocysteine
Similarity Belongs to the class I-like SAM-binding methyltransferase superfamily. Spermidine/spermine synthase family.

Gene Ontology [?]

GO:0030750; Molecular function: putrescine N-methyltransferase activity.
GO:0032259; Biological process: methylation.
GO:0046500; Biological process: S-adenosylmethionine metabolic process.

Keywords [?]

Features [?]

From: PS51615
Key     From     To       Description   Tag   Condition   FTGroup
REGION     201     202       S-adenosyl-L-methionine binding        
ACT_SITE     220     220       Proton acceptor     D  
BINDING     95     95       S-adenosyl-L-methionine     Q  
BINDING     170     170       S-adenosyl-L-methionine     E  
BINDING     289     289       S-adenosyl-L-methionine     Y  

Additional information [?]

Size range unlimited amino acids
Related rules None
Repeats 1
Topology Undefined
Example O48659 (SPDS2_HYONI)
Eukaryota; Magnoliopsida
Comments None


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UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets
Eukaryota [4]