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ProRule PRU00959


General rule information [?]

PURL https://purl.expasy.org/prosite/rule/PRU00959
Accession PRU00959
Dates 14-DEC-2011 (Created)
21-NOV-2019 (Last updated, Version 5)
Data class Domain;
Predictors
case c? <OC:Eukaryota> and <Length>=429> and <Length<=643>
PROSITE; PS51627; SAM_MT_TRM11
end case
Name tRNA (guanine(10)-N2)-methyltransferase (EC 2.1.1.214) (TRM11)
Function tRNA (guanine(10)-N(2))-methyltransferase (EC 2.1.1.214) is an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to guanine(10) in tRNA to form N(2)-methylguanine(10) in tRNA and S-adenosyl-L- homocysteine.
Scope(s) Eukaryota
Example(s) O94636 (TRM11_SCHPO);

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name + RecName: EC=2.1.1.-;

Comments [?]

SIMILARITYBelongs to the class I-like SAM-binding methyltransferase superfamily. TRM11 methyltransferase family.

Keywords [?]

Methyltransferase
RNA-binding
S-adenosyl-L-methionine
Transferase
tRNA processing
tRNA-binding

Gene Ontology [?]

GO:0000049; Molecular function:tRNA binding
GO:0016423; Molecular function:tRNA (guanine) methyltransferase activity
GO:0008033; Biological process:tRNA processing
GO:0032259; Biological process:methylation

Features [?]


Additional information [?]

Size range unlimited amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

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UniProtKB rule member sequences [?]