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ProRule PRU00968


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PURL: https://purl.expasy.org/prosite/rule/PRU00968
General rule information [?]

Accession PRU00968
Dates 06-JAN-2012 (Created)
19-NOV-2022 (Last updated, Version )
Data class Domain;
Predictors PROSITE; PS51002; CYTB_NTER
Name Cytochrome b/b6 N-terminal region
Function The cytochrome b/b6 are transmembrane proteins containing to protohemes responsible for vectorial electron transfer.
Scope(s) Eukaryota
Bacteria
Example(s) P00163;

Propagated annotation [?]

Comments [?]

SIMILARITYBelongs to the cytochrome b family.

Keywords [?]

Heme
Iron
Metal-binding
end case
Membrane
Transmembrane
Transmembrane helix
Transport
Electron transport

Gene Ontology [?]

GO:0016491; Molecular function:oxidoreductase activity
GO:0016020; Cellular component:membrane
GO:0006810; Biological process:transport
GO:0022900; Biological process:electron transport chain
case <FTGroup:1>
GO:0046872; Molecular function:metal ion binding

Cross-references [?]

General Transmembrane; -; 5;

Features [?]

From: PS51002
Key From To Description Tag Condition FTGroup
TRANSMEM 33 53 /note="Helical"
TRANSMEM 86 106 /note="Helical"
TRANSMEM 117 137 /note="Helical"
TRANSMEM 152 172 /note="Helical"
TRANSMEM 180 201 /note="Helical"
case <AnyFeature:PS51003>
BINDING 83 83 /ligand="heme b"
/ligand_id="ChEBI:CHEBI:60344"
/ligand_label="b562"
/ligand_part="Fe"
/ligand_part_id="ChEBI:CHEBI:18248"
/note="axial binding residue"		 H 1
BINDING 97 97 /ligand="heme b"
/ligand_id="ChEBI:CHEBI:60344"
/ligand_label="b566"
/ligand_part="Fe"
/ligand_part_id="ChEBI:CHEBI:18248"
/note="axial binding residue"		 H 1
BINDING 184 184 /ligand="heme b"
/ligand_id="ChEBI:CHEBI:60344"
/ligand_label="b562"
/ligand_part="Fe"
/ligand_part_id="ChEBI:CHEBI:18248"
/note="axial binding residue"		 H 1
BINDING 199 199 /ligand="heme b"
/ligand_id="ChEBI:CHEBI:60344"
/ligand_label="b566"
/ligand_part="Fe"
/ligand_part_id="ChEBI:CHEBI:18248"
/note="axial binding residue"		 H 1
else
BINDING 83 83 /ligand="heme"
/ligand_id="ChEBI:CHEBI:30413"
/ligand_label="2"
/ligand_part="Fe"
/ligand_part_id="ChEBI:CHEBI:18248"
/note="axial binding residue"		 H 1
BINDING 97 97 /ligand="heme"
/ligand_id="ChEBI:CHEBI:30413"
/ligand_label="1"
/ligand_part="Fe"
/ligand_part_id="ChEBI:CHEBI:18248"
/note="axial binding residue"		 H 1
BINDING 184 184 /ligand="heme"
/ligand_id="ChEBI:CHEBI:30413"
/ligand_label="2"
/ligand_part="Fe"
/ligand_part_id="ChEBI:CHEBI:18248"
/note="axial binding residue"		 H 1
BINDING 199 199 /ligand="heme"
/ligand_id="ChEBI:CHEBI:30413"
/ligand_label="1"
/ligand_part="Fe"
/ligand_part_id="ChEBI:CHEBI:18248"
/note="axial binding residue"		 H 1
end case

Additional information [?]

Size range 167-239 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]