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annotation rule: PRU00968

General rule information [?]

Accession PRU00968
Dates 6-JAN-2012 (Created)
21-NOV-2019 (Last updated, Version 6)
Data class Domain
Predictors PROSITE; PS51002; CYTB_NTER
Name Cytochrome b/b6 N-terminal region
Function The cytochrome b/b6 are transmembrane proteins containing to protohemes responsible for vectorial electron transfer.

Propagated annotation [?]


Comments [?]

Similarity Belongs to the cytochrome b family.

Computed features [?]

General Transmembrane; -; 5;

Gene Ontology [?]

GO:0016491; Molecular function: oxidoreductase activity.
GO:0016020; Cellular component: membrane.
GO:0016021; Cellular component: integral component of membrane.
GO:0006810; Biological process: transport.
GO:0022900; Biological process: electron transport chain.
case <FTGroup:1>
GO:0046872; Molecular function: metal ion binding.

Keywords [?]

Heme
Iron
Metal-binding
end case

Membrane
Transmembrane
Transmembrane helix
Transport
Electron transport

Features [?]

From: PS51002
Key     From     To       Description   Tag   Condition   FTGroup
TRANSMEM     33     53       Helical        
TRANSMEM     86     106       Helical        
TRANSMEM     117     137       Helical        
TRANSMEM     152     172       Helical        
TRANSMEM     180     201       Helical        
case <AnyFeature:PS51003>
METAL     83     83       Iron 1 (heme b562 axial ligand)     H   1
METAL     97     97       Iron 2 (heme b566 axial ligand)     H   1
METAL     184     184       Iron 1 (heme b562 axial ligand)     H   1
METAL     199     199       Iron 2 (heme b566 axial ligand)     H   1
else
METAL     83     83       Iron (heme 2 axial ligand)     H   1
METAL     97     97       Iron (heme 1 axial ligand)     H   1
METAL     184     184       Iron (heme 2 axial ligand)     H   1
METAL     199     199       Iron (heme 1 axial ligand)     H   1
end case


Additional information [?]

Size range 167-239 amino acids
Related rules None
Repeats 1
Topology Undefined
Example P00163 (CYB_YEAST)
Scope
Eukaryota
Bacteria
Comments None

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.


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UniProtKB rule member sequences [?]