ProRule PRU00968
General rule information
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| PURL | https://purl.expasy.org/prosite/rule/PRU00968 |
| Accession | PRU00968 |
| Dates | 6-JAN-2012 (Created)
19-NOV-2022 (Last updated, Version 9) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51002; CYTB_NTER |
Name | Cytochrome b/b6 N-terminal region |
| Function | The cytochrome b/b6 are transmembrane proteins containing to protohemes responsible for vectorial electron transfer. |
| Scope(s) |
Eukaryota Bacteria |
| Example(s) | P00163 (CYB_YEAST); |
Propagated annotation
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Comments
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| SIMILARITY | Belongs to the cytochrome b family. |
Keywords
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| Heme | |
| Iron | |
| Metal-binding | |
| end case | |
| Membrane | |
| Transmembrane | |
| Transmembrane helix | |
| Transport | |
| Electron transport | |
Gene Ontology
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| GO:0016491; Molecular function:oxidoreductase activity | |
| GO:0016020; Cellular component:membrane | |
| GO:0006810; Biological process:transport | |
| GO:0022900; Biological process:electron transport chain | |
| case <FTGroup:1> | |
| GO:0046872; Molecular function:metal ion binding | |
Cross-references
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| General | Transmembrane; -; 5; |
Features
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| From: PS51002 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| TRANSMEM | 33 | 53 | /note="Helical" | |||||||||
| TRANSMEM | 86 | 106 | /note="Helical" | |||||||||
| TRANSMEM | 117 | 137 | /note="Helical" | |||||||||
| TRANSMEM | 152 | 172 | /note="Helical" | |||||||||
| TRANSMEM | 180 | 201 | /note="Helical" | |||||||||
| case <AnyFeature:PS51003> | ||||||||||||
| BINDING | 83 | 83 | /ligand="heme b" /ligand_id="ChEBI:CHEBI:60344" /ligand_label="b562" /ligand_part="Fe" /ligand_part_id="ChEBI:CHEBI:18248" /note="axial binding residue" |
H | 1 | |||||||
| BINDING | 97 | 97 | /ligand="heme b" /ligand_id="ChEBI:CHEBI:60344" /ligand_label="b566" /ligand_part="Fe" /ligand_part_id="ChEBI:CHEBI:18248" /note="axial binding residue" |
H | 1 | |||||||
| BINDING | 184 | 184 | /ligand="heme b" /ligand_id="ChEBI:CHEBI:60344" /ligand_label="b562" /ligand_part="Fe" /ligand_part_id="ChEBI:CHEBI:18248" /note="axial binding residue" |
H | 1 | |||||||
| BINDING | 199 | 199 | /ligand="heme b" /ligand_id="ChEBI:CHEBI:60344" /ligand_label="b566" /ligand_part="Fe" /ligand_part_id="ChEBI:CHEBI:18248" /note="axial binding residue" |
H | 1 | |||||||
| else | ||||||||||||
| BINDING | 83 | 83 | /ligand="heme" /ligand_id="ChEBI:CHEBI:30413" /ligand_label="2" /ligand_part="Fe" /ligand_part_id="ChEBI:CHEBI:18248" /note="axial binding residue" |
H | 1 | |||||||
| BINDING | 97 | 97 | /ligand="heme" /ligand_id="ChEBI:CHEBI:30413" /ligand_label="1" /ligand_part="Fe" /ligand_part_id="ChEBI:CHEBI:18248" /note="axial binding residue" |
H | 1 | |||||||
| BINDING | 184 | 184 | /ligand="heme" /ligand_id="ChEBI:CHEBI:30413" /ligand_label="2" /ligand_part="Fe" /ligand_part_id="ChEBI:CHEBI:18248" /note="axial binding residue" |
H | 1 | |||||||
| BINDING | 199 | 199 | /ligand="heme" /ligand_id="ChEBI:CHEBI:30413" /ligand_label="1" /ligand_part="Fe" /ligand_part_id="ChEBI:CHEBI:18248" /note="axial binding residue" |
H | 1 | |||||||
| end case | ||||||||||||
Additional information
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| Size range | 167-239 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Archaea [2] Bacteria [68] Eukaryota [1857] All [ 1927 ]
- Retrieve set of proteins with 3D structure for this domain