PRU00977

Accession	PRU00977
Dates	21-JUN-2012 (Created) 21-NOV-2019 (Last updated, Version 4)

Data class

Domain

Predictors

PROSITE; PS50164; GIY_YIG

Name	GIY-YIG domain

Function

The GIY-YIG superfamily groups together nucleases characterized by the presence of a domain of typically ~100 amino acids, with two short motifs "GIY" and "YIG" in the N-terminal part, followed by an Arg residue in the center and a Glu residue in the C-terminal part.

GO:0090305; Biological process: nucleic acid phosphodiester bond hydrolysis.

From: PS50164

Key

From

To

Description

Tag

Condition

FTGroup

DOMAIN

from

to

GIY-YIG #

Size range	64-129 amino acids
Related rules	None
Repeats	1
Topology	Undefined
Example	B4TYW7 (UVRC_SALSV)
Scope	Bacteria Eukaryota Archaea; Euryarchaeota Viruses
Comments	None

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

View rule in raw text format (no links)

• UniProtKB/Swiss-Prot sets
  

  Archaea	[18]
  Bacteria	[723]
  Eukaryota	[76]
  Viruses	[14]
  All	[ 831 ]

  
  
• Retrieve set of proteins with 3D structure for this domain