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annotation rule: PRU00978

General rule information [?]

Accession PRU00978
Dates 20-JUN-2012 (Created)
21-NOV-2019 (Last updated, Version 19)
Data class Domain
Predictors PROSITE; PS50217; BZIP
Name Basic-leucine zipper (bZIP) domain
Function The bZIP superfamily of eukaryotic DNA-binding transcription factors groups together proteins that contain a basic region mediating sequence- specific DNA-binding followed by a leucine zipper required for dimerization.

Propagated annotation [?]

Comments [?]

Subcellular location Nucleus.

Cross-references [?]


Gene Ontology [?]

GO:0043565; Molecular function: sequence-specific DNA binding.
GO:0003700; Molecular function: DNA-binding transcription factor activity.
GO:0005634; Cellular component: nucleus.

Keywords [?]

Features [?]

From: PS50217
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       bZIP #        
REGION     $1     $2       Basic motif #        
REGION     $3     $4       Leucine-zipper #        

Additional information [?]

Size range 26-74 amino acids
Related rules None
Repeats 1
Topology Undefined
Example P01102 (FOS_MSVFB)
Comments None


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets
Eukaryota [453]
Viruses [11]
All [ 464 ]