ProRule PRU00978
General rule information
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| PURL | https://purl.expasy.org/prosite/rule/PRU00978 |
| Accession | PRU00978 |
| Dates | 20-JUN-2012 (Created)
21-NOV-2019 (Last updated, Version 19) |
| Data class | Domain; |
| Predictors |
PROSITE; PS50217; BZIP |
Name | Basic-leucine zipper (bZIP) domain |
| Function | The bZIP superfamily of eukaryotic DNA-binding transcription factors groups together proteins that contain a basic region mediating sequence- specific DNA-binding followed by a leucine zipper required for dimerization. |
| Scope(s) |
Eukaryota Viruses |
| Example(s) | P01102 (FOS_MSVFB); |
Propagated annotation
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Comments
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| SUBCELLULAR LOCATION | Nucleus. |
Keywords
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Gene Ontology
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| GO:0043565; Molecular function:sequence-specific DNA binding |
| GO:0003700; Molecular function:DNA-binding transcription factor activity |
| GO:0005634; Cellular component:nucleus |
Cross-references
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| PROSITE | PS00036; BZIP_BASIC; 0-1; |
Features
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| From: PS50217 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="bZIP #" | |||||||||
| From: PS50217 :([KR]).*?([KR])[^KR]*?([LI])(?:.{6}[LI])*.{6}([LI]) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| REGION | $1 | $2 | /note="Basic motif #" | |||||||||
| REGION | $3 | $4 | /note="Leucine-zipper #" | |||||||||
Additional information
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| Size range | 26-74 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [474] Viruses [11] All [ 485 ]
- Retrieve set of proteins with 3D structure for this domain