ProRule PRU00979
General rule information
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| PURL | https://purl.expasy.org/prosite/rule/PRU00979 |
| Accession | PRU00979 |
| Dates | 12-OCT-2012 (Created)
21-NOV-2019 (Last updated, Version 4) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51647; CYSTATIN_KININOGEN |
Name | Kininogen-type cystatin domain |
| Function | Kininogens are multifunctional and multidomain glycoproteins related to cystatins. |
| Scope(s) |
Eukaryota Eutheria |
| Example(s) | P08934 (KNG1_RAT); |
Propagated annotation
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Keywords
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| case <FTTag:disulf> | |
| Disulfide bond | |
| end case | |
| Protease inhibitor | |
| Thiol protease inhibitor | |
Gene Ontology
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| GO:0004869; Molecular function:cysteine-type endopeptidase inhibitor activity |
| GO:0010466; Biological process:negative regulation of peptidase activity |
Features
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| From: PS51647 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="Cystatin kininogen-type #" | |||||||||
| DISULFID | 56 | 67 | disulf | C-x*-C | ||||||||
| DISULFID | 56 | 69 | disulf | C-x*-C | ||||||||
| DISULFID | 80 | 99 | disulf | C-x*-C | ||||||||
Additional information
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| Size range | 94-115 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 3 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [9] All [ 9 ]
- Retrieve set of proteins with 3D structure for this domain