ProRule PRU00981
General rule information
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| PURL | https://purl.expasy.org/prosite/rule/PRU00981 |
| Accession | PRU00981 |
| Dates | 5-JUL-2012 (Created)
21-NOV-2019 (Last updated, Version 6) |
| Data class | Domain; |
| Predictors |
PROSITE; PS50888; BHLH |
Name | Myc-type, basic helix-loop-helix (bHLH) domain |
| Function | Fill in |
| Scope(s) |
Eukaryota Viruses Retroviridae |
| Example(s) | Q9W6C8 (NDF2_DANRE); |
Propagated annotation
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Comments
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| SUBCELLULAR LOCATION | Nucleus. |
| case not <FTTag:basic> | |
| CAUTION | Contains a degenerate basic motif not likely to bind DNA. |
| end case | |
Keywords
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| Nucleus | |
| case <FTTag:basic> | |
| DNA-binding | |
| end case | |
| Transcription | |
| Transcription regulation | |
Gene Ontology
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| GO:0005634; Cellular component:nucleus |
Features
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| From: PS50888 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="bHLH #" | |||||||||
| REGION | 15 | to | /note="Helix-loop-helix motif #" | |||||||||
| case <Feature:PS50888:1-14=x(0,)-[RK]-x(0,)-[RK]-x(0,)-[RK]-x(0,)-[RK]-x(0,)> | ||||||||||||
| REGION | from | 14 | /note="Basic motif #" | basic | ||||||||
| else | ||||||||||||
| REGION | from | 14 | /note="Basic motif #; degenerate" | |||||||||
| end case | ||||||||||||
Additional information
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| Size range | 38-115 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [838] Viruses [8] All [ 846 ]
- Retrieve set of proteins with 3D structure for this domain