ProRule PRU00983
General rule information
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| Accession | PRU00983 |
| Dates | 26-APR-2016 (Created)
6-JAN-2020 (Last updated, Version 4) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51650; C2_DOCK |
Name | C2 DOCK-type domain |
| Function | The ~200 residue DOCK-type C2 domain is located toward the N- terminus and interacts with phosphatidylinositol 3,4,5-trisphosphate [PtdIns(3,4,5)P3] to mediate signalling and membrane localization. |
| Scope(s) |
Eukaryota |
| Example(s) | Q8C3J5 (DOCK2_MOUSE); |
Propagated annotation
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Comments
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| SIMILARITY | Belongs to the DOCK family. |
Features
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| From: PS51650 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="C2 DOCK-type #" | |||||||||
Additional information
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| Size range | 150-195 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [24] All [ 24 ]
- Retrieve set of proteins with 3D structure for this domain