PROSITE logo

ProRule PRU00989


General rule information [?]

Accession PRU00989
Dates 3-MAY-2016 (Created)
8-OCT-2024 (Last updated, Version 7)
Data class Domain;
Predictors PROSITE; PS51656; 4FE4S
Name 4Fe-4S domain
Function The low-potential [4Fe-4S]2(+)/1(+) cluster is involved in the reductive reactivation of CoFeSP and is able to transfer electrons to cob(II)amide from NiFe-containing carbon monoxyde dehydrogenase (CODH), pyruvate:ferredoxin oxydoreductase or reduced ferredoxins.
Scope(s) Bacteria
Archaea
Methanobacteriati
Example(s) Q8PV87 (ACDG2_METMA);

Propagated annotation [?]

Comments [?]

case <FTGroup:1>
COFACTOR Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883; Note=Binds #1 [4Fe-4S] cluster.;
end case

Keywords [?]

4Fe-4S
Iron
Iron-sulfur
Metal-binding
end case

Gene Ontology [?]

case <FTGroup:1>
GO:0051539; Molecular function:4 iron, 4 sulfur cluster binding
GO:0046872; Molecular function:metal ion binding

Features [?]

From: PS51656
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="4Fe-4S #"
case not <Triggered>
BINDING 18 18 /ligand="[4Fe-4S] cluster"
/ligand_id="ChEBI:CHEBI:49883"		 C 1
BINDING 21 21 /ligand="[4Fe-4S] cluster"
/ligand_id="ChEBI:CHEBI:49883"		 C 1
BINDING 26 26 /ligand="[4Fe-4S] cluster"
/ligand_id="ChEBI:CHEBI:49883"		 C 1
BINDING 43 43 /ligand="[4Fe-4S] cluster"
/ligand_id="ChEBI:CHEBI:49883"		 C 1
end case

Additional information [?]

Size range 49-74 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



View rule in raw text format (no links)

UniProtKB rule member sequences [?]