PROSITE logo
Black ribbon
We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU01017


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01017
General rule information [?]

Accession PRU01017
Dates 23-JUL-2013 (Created)
03-SEP-2024 (Last updated, Version 6)
Data class Domain;
Predictors PROSITE; PS51680; SAM_MT_DRM
Name SAM-dependent methyltransferase DRM-type domain
Function Domains rearranged methylase (DRM) C5 methyltransferase
Scope(s) Eukaryota
Arabidopsis
Example(s) Q9M548;

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name + RecName: EC=2.1.1.37;

Comments [?]

CATALYTIC ACTIVITY Reaction=a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5- methyl-2'-deoxycytidine in DNA + S-adenosyl-L-homocysteine + H(+); Xref=Rhea:RHEA:13681, Rhea:RHEA-COMP:11369, Rhea:RHEA-COMP:11370, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:85452, ChEBI:CHEBI:85454; EC=2.1.1.37;
SIMILARITYBelongs to the class I-like SAM-binding methyltransferase superfamily. DRM-methyltransferase family.

Keywords [?]

Methyltransferase
S-adenosyl-L-methionine
Transferase

Features [?]

From: PS51680
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="SAM-dependent MTase DRM-type"

Additional information [?]

Size range 322-342 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]