PROSITE logo
Black ribbon
We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU01041


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01041
General rule information [?]

Accession PRU01041
Dates 25-AUG-2014 (Created)
19-NOV-2022 (Last updated, Version 9)
Data class Domain;
Predictors PROSITE; PS51704; GP_PDE
Name GP-PDE domain
Function GD-PDEs are involved in glycerol metabolism and catalyze the reaction of glycerophosphodiester and water to alcohol and sn-glycerol-3- phosphate.
Scope(s) Eukaryota
Bacteria
Example(s) Q9SZ11;

Propagated annotation [?]

Comments [?]

case <FTGroup:1>
COFACTOR Name=a divalent metal cation; Xref=CHEBI:60240;
end case

Keywords [?]

Hydrolase
case <FTGroup:1>
Metal-binding
end case

Gene Ontology [?]

GO:0006071; Biological process:glycerol metabolic process
GO:0008889; Molecular function:glycerophosphodiester phosphodiesterase activity

Features [?]

From: PS51704
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="GP-PDE #"
BINDING 33 33 /ligand="a divalent metal cation"
/ligand_id="ChEBI:CHEBI:60240"		 E 1
BINDING 35 35 /ligand="a divalent metal cation"
/ligand_id="ChEBI:CHEBI:60240"		 D 1
BINDING 48 48 /ligand="a divalent metal cation"
/ligand_id="ChEBI:CHEBI:60240"		 H 1

Additional information [?]

Size range 223-356 amino acids
Related rules None
Fusion None
Repeats 1-2
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]