ProRule PRU01043
General rule information
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Accession | PRU01043 |
Dates | 25-MAR-2014 (Created)
19-NOV-2022 (Last updated, Version 14) |
Data class | Domain; |
Predictors |
PROSITE; PS51706; G_ENGB |
Name | EngB-type guanine nucleotide-binding (G) domain |
Function | Proteins of the EngB-type GTPase family are involved in the biogenesis of ribosomes and are essential for the survival of a wide range of bacteria. |
Scope(s) |
Bacteria Archaea Euryarchaeota Eukaryota |
Example(s) | P38424 (ENGB_BACSU); |
Propagated annotation
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Comments
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case <FTGroup:2> | |
COFACTOR | Name=Mg(2+); Xref=ChEBI:CHEBI:18420; |
end case | |
SIMILARITY | Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. |
Keywords
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case <FTGroup:1> | |
GTP-binding | |
Nucleotide-binding | |
end case | |
case <FTGroup:2> | |
Magnesium | |
Metal-binding | |
end case |
Gene Ontology
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case <FTGroup:1> | |
GO:0005525; Molecular function:GTP binding | |
GO:0003924; Molecular function:GTPase activity | |
end case | |
case <FTGroup:2> | |
GO:0000287; Molecular function:magnesium ion binding | |
GO:0046872; Molecular function:metal ion binding | |
end case |
Features
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From: PS51706 | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
DOMAIN | from | to | /note="EngB-type G #" | |||||||||
BINDING | 9 | 16 | /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565" |
G-x(4)-G-K-[ST] | 1 | |||||||
BINDING | 36 | 40 | /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565" |
x(2)-[ST]-x(2) | 1 | |||||||
BINDING | 55 | 58 | /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565" |
D-x(2)-G | 1 | |||||||
BINDING | 122 | 125 | /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565" |
[NT]-K-x-D | 1 | |||||||
BINDING | 157 | 159 | /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565" |
1 | ||||||||
BINDING | 16 | 16 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420" |
[ST] | 2 | |||||||
BINDING | 38 | 38 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420" |
[ST] | 2 |
Additional information
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Size range | 153-218 amino acids |
Related rules |
None |
Fusion | None |
Repeats | 1 |
Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Archaea [15] Bacteria [526] Eukaryota [7] All [ 548 ]
- Retrieve set of proteins with 3D structure for this domain