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ProRule PRU01043


General rule information [?]

PURL https://purl.expasy.org/prosite/rule/PRU01043
Accession PRU01043
Dates 25-MAR-2014 (Created)
8-OCT-2024 (Last updated, Version 15)
Data class Domain;
Predictors PROSITE; PS51706; G_ENGB
Name EngB-type guanine nucleotide-binding (G) domain
Function Proteins of the EngB-type GTPase family are involved in the biogenesis of ribosomes and are essential for the survival of a wide range of bacteria.
Scope(s) Bacteria
Archaea
Methanobacteriati
Eukaryota
Example(s) P38424 (ENGB_BACSU);

Propagated annotation [?]

Comments [?]

case <FTGroup:2>
COFACTOR Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
end case
SIMILARITYBelongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.

Keywords [?]

case <FTGroup:1>
GTP-binding
Nucleotide-binding
end case
case <FTGroup:2>
Magnesium
Metal-binding
end case

Gene Ontology [?]

case <FTGroup:1>
GO:0005525; Molecular function:GTP binding
GO:0003924; Molecular function:GTPase activity
end case
case <FTGroup:2>
GO:0000287; Molecular function:magnesium ion binding
GO:0046872; Molecular function:metal ion binding
end case

Features [?]

From: PS51706
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="EngB-type G #"
BINDING 9 16 /ligand="GTP"
/ligand_id="ChEBI:CHEBI:37565"		 G-x(4)-G-K-[ST] 1
BINDING 36 40 /ligand="GTP"
/ligand_id="ChEBI:CHEBI:37565"		 x(2)-[ST]-x(2) 1
BINDING 55 58 /ligand="GTP"
/ligand_id="ChEBI:CHEBI:37565"		 D-x(2)-G 1
BINDING 122 125 /ligand="GTP"
/ligand_id="ChEBI:CHEBI:37565"		 [NT]-K-x-D 1
BINDING 157 159 /ligand="GTP"
/ligand_id="ChEBI:CHEBI:37565"		 1
BINDING 16 16 /ligand="Mg(2+)"
/ligand_id="ChEBI:CHEBI:18420"		 [ST] 2
BINDING 38 38 /ligand="Mg(2+)"
/ligand_id="ChEBI:CHEBI:18420"		 [ST] 2

Additional information [?]

Size range 153-218 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



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UniProtKB rule member sequences [?]