We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.

ProRule PRU01043

View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01043

General rule information [?]

Accession	PRU01043
Dates	25-MAR-2014 (Created) 08-OCT-2024 (Last updated, Version 16)
Data class	Domain;
Predictors	PROSITE; PS51706; G_ENGB
Name	EngB-type guanine nucleotide-binding (G) domain
Function	Proteins of the EngB-type GTPase family are involved in the biogenesis of ribosomes and are essential for the survival of a wide range of bacteria.
Scope(s)	Bacteria Archaea Methanobacteriati Eukaryota
Example(s)	P38424;

Propagated annotation [?]

Comments [?]

case <FTGroup:2>
COFACTOR	Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
end case
SIMILARITY	Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.

Keywords [?]

case <FTGroup:1>
GTP-binding
Nucleotide-binding
end case
case <FTGroup:2>
Magnesium
Metal-binding
end case

Gene Ontology [?]

case <FTGroup:1>
GO:0005525; Molecular function:GTP binding
GO:0003924; Molecular function:GTPase activity
end case
case <FTGroup:2>
GO:0000287; Molecular function:magnesium ion binding
GO:0046872; Molecular function:metal ion binding
end case

Features [?]

From: PS51706

Key

From

Description

Tag

Condition

FTGroup

DOMAIN

from

/note="EngB-type G #"

BINDING