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General rule information [?]

Accession PRU01047
Dates 14-MAR-2014 (Created)
19-NOV-2022 (Last updated, Version 20)
Data class Domain
Predictors PROSITE; PS51710; G_OBG
Name OBG-type guanine nucleotide-binding (G) domain
Function Within the translation factor-related (TRAFAC) class of P-loop GTPases, the OBG family comprises a group of high-molecular mass GTPases conserved from bacteria to eukaryotes.

Propagated annotation [?]

Comments [?]

case <FTGroup:2>
Cofactor Mg(2+)
end case

Similarity Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

Gene Ontology [?]

case <FTGroup:1>
GO:0005525; Molecular function: GTP binding.
GO:0003924; Molecular function: GTPase activity.
end case

case <FTGroup:2>
GO:0005524; Molecular function: ATP binding.
GO:0016887; Molecular function: ATP hydrolysis activity.
end case

case <FTGroup:3>
GO:0046872; Molecular function: metal ion binding.
GO:0000287; Molecular function: magnesium ion binding.
end case

Keywords [?]

case <FTGroup:1>
end case

case <FTGroup:2>
end case

case <FTGroup:1> and <FTGroup:2>
end case

case <FTGroup:3>
end case

Features [?]

From: PS51710
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       OBG-type G #        
BINDING     7     14       /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565     G-x(4)-G-K-[ST]   1
BINDING     32     36       /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565     x(2)-[ST]-x(2)   1
BINDING     54     57       /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565     D-x(2)-G   1
BINDING     126     129       /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565     [NT]-K-x-D   1
BINDING     156     158       /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565         1
BINDING     7     14       /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616     G-x(4)-G-K-[ST]   2
BINDING     32     36       /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616     x(2)-[ST]-x(2)   2
BINDING     54     57       /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616     D-x(2)-G   2
BINDING     126     129       /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616     N-x(2)-[EQ]   2
BINDING     156     158       /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616         2
BINDING     14     14       /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420     [ST]   3
BINDING     34     34       /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420     [ST]   3

Additional information [?]

Size range 51-280 amino acids
Related rules None
Repeats 1
Topology Undefined
Examples Q72HR4 (OBG_THET2); Q9NTK5 (OLA1_HUMAN): [Recover all]
Archaea; Euryarchaeota
Comments None


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UniProtKB rule member sequences [?]