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ProRule PRU01047


General rule information [?]

PURL https://purl.expasy.org/prosite/rule/PRU01047
Accession PRU01047
Dates 14-MAR-2014 (Created)
8-OCT-2024 (Last updated, Version 21)
Data class Domain;
Predictors PROSITE; PS51710; G_OBG
Name OBG-type guanine nucleotide-binding (G) domain
Function Within the translation factor-related (TRAFAC) class of P-loop GTPases, the OBG family comprises a group of high-molecular mass GTPases conserved from bacteria to eukaryotes.
Scope(s) Bacteria
Eukaryota
Archaea
Methanobacteriati
Example(s) Q72HR4 (OBG_THET2); Q9NTK5 (OLA1_HUMAN);

Propagated annotation [?]

Comments [?]

case <FTGroup:2>
COFACTOR Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
end case
SIMILARITYBelongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

Keywords [?]

case <FTGroup:1>
GTP-binding
end case
case <FTGroup:2>
ATP-binding
end case
case <FTGroup:1> and <FTGroup:2>
Nucleotide-binding
end case
case <FTGroup:3>
Magnesium
Metal-binding
end case

Gene Ontology [?]

case <FTGroup:1>
GO:0005525; Molecular function:GTP binding
GO:0003924; Molecular function:GTPase activity
end case
case <FTGroup:2>
GO:0005524; Molecular function:ATP binding
GO:0016887; Molecular function:ATP hydrolysis activity
end case
case <FTGroup:3>
GO:0046872; Molecular function:metal ion binding
GO:0000287; Molecular function:magnesium ion binding
end case

Features [?]

From: PS51710
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="OBG-type G #"
BINDING 7 14 /ligand="GTP"
/ligand_id="ChEBI:CHEBI:37565"		 G-x(4)-G-K-[ST] 1
BINDING 32 36 /ligand="GTP"
/ligand_id="ChEBI:CHEBI:37565"		 x(2)-[ST]-x(2) 1
BINDING 54 57 /ligand="GTP"
/ligand_id="ChEBI:CHEBI:37565"		 D-x(2)-G 1
BINDING 126 129 /ligand="GTP"
/ligand_id="ChEBI:CHEBI:37565"		 [NT]-K-x-D 1
BINDING 156 158 /ligand="GTP"
/ligand_id="ChEBI:CHEBI:37565"		 1
BINDING 7 14 /ligand="ATP"
/ligand_id="ChEBI:CHEBI:30616"		 G-x(4)-G-K-[ST] 2
BINDING 32 36 /ligand="ATP"
/ligand_id="ChEBI:CHEBI:30616"		 x(2)-[ST]-x(2) 2
BINDING 54 57 /ligand="ATP"
/ligand_id="ChEBI:CHEBI:30616"		 D-x(2)-G 2
BINDING 126 129 /ligand="ATP"
/ligand_id="ChEBI:CHEBI:30616"		 N-x(2)-[EQ] 2
BINDING 156 158 /ligand="ATP"
/ligand_id="ChEBI:CHEBI:30616"		 2
BINDING 14 14 /ligand="Mg(2+)"
/ligand_id="ChEBI:CHEBI:18420"		 [ST] 3
BINDING 34 34 /ligand="Mg(2+)"
/ligand_id="ChEBI:CHEBI:18420"		 [ST] 3

Additional information [?]

Size range 51-280 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



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UniProtKB rule member sequences [?]