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ProRule PRU01047
General rule information
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Accession | PRU01047 |
Dates | 14-MAR-2014 (Created)
19-NOV-2022 (Last updated, Version 20) |
Data class | Domain; |
Predictors |
PROSITE; PS51710; G_OBG |
Name | OBG-type guanine nucleotide-binding (G) domain |
Function | Within the translation factor-related (TRAFAC) class of P-loop GTPases, the OBG family comprises a group of high-molecular mass GTPases conserved from bacteria to eukaryotes. |
Scope(s) |
Bacteria Eukaryota Archaea Euryarchaeota |
Example(s) | Q72HR4 (OBG_THET2); Q9NTK5 (OLA1_HUMAN); |
Propagated annotation
[?]
Comments
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case <FTGroup:2> | |
COFACTOR | Name=Mg(2+); Xref=ChEBI:CHEBI:18420; |
end case | |
SIMILARITY | Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. |
Keywords
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case <FTGroup:1> | |
GTP-binding | |
end case | |
case <FTGroup:2> | |
ATP-binding | |
end case | |
case <FTGroup:1> and <FTGroup:2> | |
Nucleotide-binding | |
end case | |
case <FTGroup:3> | |
Magnesium | |
Metal-binding | |
end case |
Gene Ontology
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case <FTGroup:1> | |
GO:0005525; Molecular function:GTP binding | |
GO:0003924; Molecular function:GTPase activity | |
end case | |
case <FTGroup:2> | |
GO:0005524; Molecular function:ATP binding | |
GO:0016887; Molecular function:ATP hydrolysis activity | |
end case | |
case <FTGroup:3> | |
GO:0046872; Molecular function:metal ion binding | |
GO:0000287; Molecular function:magnesium ion binding | |
end case |
Features
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From: PS51710 | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
DOMAIN | from | to | /note="OBG-type G #" | |||||||||
BINDING | 7 | 14 | /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565" |
G-x(4)-G-K-[ST] | 1 | |||||||
BINDING | 32 | 36 | /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565" |
x(2)-[ST]-x(2) | 1 | |||||||
BINDING | 54 | 57 | /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565" |
D-x(2)-G | 1 | |||||||
BINDING | 126 | 129 | /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565" |
[NT]-K-x-D | 1 | |||||||
BINDING | 156 | 158 | /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565" |
1 | ||||||||
BINDING | 7 | 14 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616" |
G-x(4)-G-K-[ST] | 2 | |||||||
BINDING | 32 | 36 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616" |
x(2)-[ST]-x(2) | 2 | |||||||
BINDING | 54 | 57 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616" |
D-x(2)-G | 2 | |||||||
BINDING | 126 | 129 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616" |
N-x(2)-[EQ] | 2 | |||||||
BINDING | 156 | 158 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616" |
2 | ||||||||
BINDING | 14 | 14 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420" |
[ST] | 3 | |||||||
BINDING | 34 | 34 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420" |
[ST] | 3 |
Additional information
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Size range | 51-280 amino acids |
Related rules |
None |
Fusion | None |
Repeats | 1 |
Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Archaea [4] Bacteria [788] Eukaryota [72] All [ 864 ]
- Retrieve set of proteins with 3D structure for this domain