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annotation rule: PRU01047

General rule information [?]

Accession PRU01047
Dates 14-MAR-2014 (Created)
22-NOV-2019 (Last updated, Version 16)
Data class Domain
Predictors PROSITE; PS51710; G_OBG
Name OBG-type guanine nucleotide-binding (G) domain
Function Within the translation factor-related (TRAFAC) class of P-loop GTPases, the OBG family comprises a group of high-molecular mass GTPases conserved from bacteria to eukaryotes.

Propagated annotation [?]

Comments [?]

case <FTGroup:2>
Cofactor Mg(2+)
end case

Similarity Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

Gene Ontology [?]

case <FTGroup:1>
GO:0005525; Molecular function: GTP binding.
GO:0003924; Molecular function: GTPase activity.
end case

case <FTGroup:2>
GO:0005524; Molecular function: ATP binding.
GO:0016887; Molecular function: ATPase activity.
end case

case <FTGroup:3>
GO:0046872; Molecular function: metal ion binding.
GO:0000287; Molecular function: magnesium ion binding.
end case

Keywords [?]

case <FTGroup:1>
end case

case <FTGroup:2>
end case

case <FTGroup:1> and <FTGroup:2>
end case

case <FTGroup:3>
end case

Features [?]

From: PS51710
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       OBG-type G #        
NP_BIND     7     14       GTP     G-x(4)-G-K-[ST]   1
NP_BIND     32     36       GTP     x(2)-[ST]-x(2)   1
NP_BIND     54     57       GTP     D-x(2)-G   1
NP_BIND     126     129       GTP     [NT]-K-x-D   1
NP_BIND     156     158       GTP         1
NP_BIND     7     14       ATP     G-x(4)-G-K-[ST]   2
NP_BIND     32     36       ATP     x(2)-[ST]-x(2)   2
NP_BIND     54     57       ATP     D-x(2)-G   2
NP_BIND     126     129       ATP     N-x(2)-[EQ]   2
NP_BIND     156     158       ATP         2
METAL     14     14       Magnesium     [ST]   3
METAL     34     34       Magnesium     [ST]   3

Additional information [?]

Size range 51-280 amino acids
Related rules None
Repeats 1
Topology Undefined
Examples Q72HR4 (OBG_THET2); Q9NTK5 (OLA1_HUMAN): [Recover all]
Archaea; Euryarchaeota
Comments None


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UniProtKB rule member sequences [?]