PRU01047

General rule information [?]

Accession	PRU01047
Dates	14-MAR-2014 (Created) 19-NOV-2022 (Last updated, Version 20)

Data class

Domain

Predictors

PROSITE; PS51710; G_OBG

Name	OBG-type guanine nucleotide-binding (G) domain

Function

Within the translation factor-related (TRAFAC) class of P-loop GTPases, the OBG family comprises a group of high-molecular mass GTPases conserved from bacteria to eukaryotes.

Propagated annotation [?]

Comments [?]

case <FTGroup:2>

Cofactor

Mg(2+)

end case

Similarity

Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

Gene Ontology [?]

case <FTGroup:1>

GO:0005525; Molecular function: GTP binding.
GO:0003924; Molecular function: GTPase activity.

end case

case <FTGroup:2>

GO:0005524; Molecular function: ATP binding.
GO:0016887; Molecular function: ATP hydrolysis activity.

end case

case <FTGroup:3>

GO:0046872; Molecular function: metal ion binding.
GO:0000287; Molecular function: magnesium ion binding.

end case

Keywords [?]

case <FTGroup:1>

GTP-binding

end case

case <FTGroup:2>

ATP-binding

end case

case <FTGroup:1> and <FTGroup:2>

Nucleotide-binding

end case

case <FTGroup:3>

Magnesium
Metal-binding

end case

Features [?]

From: PS51710

Key From To Description Tag Condition FTGroup

DOMAIN from to OBG-type G #

BINDING 7 14 /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565 G-x(4)-G-K-[ST] 1

BINDING 32 36 /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565 x(2)-[ST]-x(2) 1

BINDING 54 57 /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565 D-x(2)-G 1

BINDING 126 129 /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565 [NT]-K-x-D 1

BINDING 156 158 /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565 1

BINDING 7 14 /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616 G-x(4)-G-K-[ST] 2

BINDING 32 36 /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616 x(2)-[ST]-x(2) 2

BINDING 54 57 /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616 D-x(2)-G 2

BINDING 126 129 /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616 N-x(2)-[EQ] 2

BINDING 156 158 /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616 2

BINDING 14 14 /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420 [ST] 3

BINDING 34 34 /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420 [ST] 3

Additional information [?]

Size range	51-280 amino acids
Related rules	None
Repeats	1
Topology	Undefined
Examples	Q72HR4 (OBG_THET2); Q9NTK5 (OLA1_HUMAN): [Recover all]
Scope	Bacteria Eukaryota Archaea; Euryarchaeota
Comments	None

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

View rule in raw text format (no links)

UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets

Archaea [4]

Bacteria [788]

Eukaryota [72]

All [ 864 ]
Retrieve set of proteins with 3D structure for this domain

Archaea	[4]
Bacteria	[788]
Eukaryota	[72]
All	[ 864 ]