We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.

ProRule PRU01049

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PURL: https://purl.expasy.org/prosite/rule/PRU01049

General rule information [?]

Accession	PRU01049
Dates	01-APR-2014 (Created) 19-NOV-2022 (Last updated, Version 11)
Data class	Domain;
Predictors	PROSITE; PS51712; G_ENGA
Name	EngA-type guanine nucleotide-binding (G) domain
Function	EngA (Essential neisserial GTPase A) proteins belong to TrmE-Era- EngA-YihA-Septin like superfamily of TRAFAC class and form a unique family of bacterial GTPases with two G domains in tandem, namely GD1 and GD2, followed by a C-terminal KH-like domain. They have been shown to interact with the bacterial ribosome and to be involved in its biogenesis.
Scope(s)	Bacteria
Example(s)	P50743;

Propagated annotation [?]

Comments [?]

SIMILARITY

Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.

Keywords [?]

GTP-binding
Nucleotide-binding
end case

Gene Ontology [?]

case <FTGroup:1>
GO:0005525; Molecular function:GTP binding
GO:0003924; Molecular function:GTPase activity

Features [?]

From: PS51712

Key

From

Description

Tag

Condition

FTGroup

DOMAIN

from

/note="EngA-type G #"

BINDING