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PRU01049


General rule information [?]

Accession PRU01049
Dates 1-APR-2014 (Created)
19-NOV-2022 (Last updated, Version 10)
Data class Domain
Predictors PROSITE; PS51712; G_ENGA
Name EngA-type guanine nucleotide-binding (G) domain
Function EngA (Essential neisserial GTPase A) proteins belong to TrmE-Era- EngA-YihA-Septin like superfamily of TRAFAC class and form a unique family of bacterial GTPases with two G domains in tandem, namely GD1 and GD2, followed by a C-terminal KH-like domain. They have been shown to interact with the bacterial ribosome and to be involved in its biogenesis.

Propagated annotation [?]


Comments [?]

Similarity Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.

Gene Ontology [?]

case <FTGroup:1>
GO:0005525; Molecular function: GTP binding.
GO:0003924; Molecular function: GTPase activity.

Keywords [?]

end case


Features [?]

From: PS51712
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       EngA-type G #        
BINDING     7     14       /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565" /ligand_label="#1     G-x(4)-G-K-[ST]   1
BINDING     33     37       /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565" /ligand_label="#1     x(2)-[ST]-x(2)   1
BINDING     54     57       /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565" /ligand_label="#1     D-x(2)-G   1
BINDING     119     122       /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565" /ligand_label="#1     N-K-x-[DE]   1
BINDING     149     151       /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565" /ligand_label="#1         1

Additional information [?]

Size range 152-194 amino acids
Related rules None
Repeats 2
Topology Undefined
Example P50743 (DER_BACSU)
Scope
Bacteria
Comments None

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



UniProtKB rule member sequences [?]