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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU01050


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01050
General rule information [?]

Accession PRU01050
Dates 14-MAY-2020 (Created)
20-MAY-2020 (Last updated, Version 3)
Data class Domain;
Predictors PROSITE; PS51713; G_ERA
Name Era-type guanine nucleotide-binding (G) domain profile
Function Era is a small G-protein widely conserved in eubacteria and eukaryotes. It is essential for bacterial cell viability and is required for the maturation of 16S rRNA and assembly of the 30S ribosomal subunit.
Scope(s) Bacteria
Eukaryota
Example(s) C0PYG8;

Propagated annotation [?]

Comments [?]

SIMILARITYBelongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. Era GTPase family.

Keywords [?]

GTP-binding
Nucleotide-binding
end case

Gene Ontology [?]

case <FTGroup:1>
GO:0005525; Molecular function:GTP binding

Features [?]

From: PS51713
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Era-type G #"
REGION 9 16 /note="G1 #" G-x(4)-G-K-S 1
REGION 35 39 /note="G2 #" x(2)-T-x(2) 1
REGION 56 59 /note="G3 #" D-x(2)-G 1
REGION 118 121 /note="G4 #" [NST]-[K]-x-[DE] 1
REGION 148 150 /note="G5 #" 1

Additional information [?]

Size range 133-276 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]