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ProRule PRU01052


General rule information [?]

Accession PRU01052
Dates 11-MAY-2020 (Created)
13-MAY-2020 (Last updated, Version 3)
Data class Domain;
Predictors PROSITE; PS51715; G_GB1_RHD3
Name GB1/RHD3-type guanine nucleotide-binding (G) domain
Function The GB1/RHD3 GTPase family contains a large G domain (~230 amino acids). The GB1/RHD3-type G domain has a low intrinsic affinity for nucleotide and often depends on nucleotide-dependent homodimerization to facilitate GTP hydrolysis.
Scope(s) Eukaryota
Example(s) Q8NHH9 (ATLA2_HUMAN);

Propagated annotation [?]

Comments [?]

SIMILARITYBelongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

Keywords [?]

GTP-binding
Hydrolase
Nucleotide-binding
end case

Gene Ontology [?]

case <Feature:PS51715:11-18=G-x(4)-G-K-[ST]> and <Feature:PS51715:67=D> and <Feature:PS51715:138-141=[ILV]-V-R-D>
GO:0005525; Molecular function:GTP binding

Features [?]

From: PS51715
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="GB1/RHD3-type G #"

Additional information [?]

Size range 205-282 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

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UniProtKB rule member sequences [?]