PROSITE logo
Black ribbon
We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU01054


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01054
General rule information [?]

Accession PRU01054
Dates 24-APR-2020 (Created)
24-APR-2020 (Last updated, Version 3)
Data class Domain;
Predictors PROSITE; PS51717; G_VLIG
Name Very large inducible GTPASE (VLIG)-type guanine nucleotide-binding (G) domain
Function The very large inducible GTPase (VLIG) family contributes to the cellular response to both type I and type II interferons (IFNs). The potential GTP-binding activity of mouse VLIG-1, the prototype VLIG, possesses a classical GTP-binding sequence motif.
Scope(s) Eukaryota
Eutheria
Example(s) Q5NCI0;

Propagated annotation [?]

Comments [?]

SIMILARITYBelongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.

Keywords [?]

GTP-binding
Nucleotide-binding

Gene Ontology [?]

GO:0005525; Molecular function:GTP binding
GO:0003924; Molecular function:GTPase activity

Features [?]

From: PS51717
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="VLIG-type G #"

Additional information [?]

Size range 230-250 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]