We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU01059
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01059
General rule information
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| Accession | PRU01059 |
| Dates | 16-JUN-2014 (Created)
22-NOV-2019 (Last updated, Version 7) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51722; G_TR_2 |
Name | Translational (tr)-type guanine nucleotide-binding (G) domain |
| Function | Translational GTPases (trGTPases) are a family of proteins in which GTPase activity is stimulated by the large ribosomal subunit. |
| Scope(s) |
Bacteria Eukaryota Archaea Viruses Mimivirus |
| Example(s) | O50293; |
Propagated annotation
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Comments
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| SIMILARITY | Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. |
Keywords
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| GTP-binding | |
| Nucleotide-binding | |
| end case | |
Gene Ontology
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| case <FTGroup:1> | |
| GO:0005525; Molecular function:GTP binding | |
| GO:0003924; Molecular function:GTPase activity | |
Features
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| From: PS51722 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="tr-type G #" | |||||||||
| REGION | 10 | 17 | /note="G1 #" | G-x(4)-G-K-[ST] | 1 | |||||||
| REGION | 52 | 56 | /note="G2 #" | x(2)-[TS]-x(2) | 1 | |||||||
| REGION | 73 | 76 | /note="G3 #" | D-x(2)-G | 1 | |||||||
| REGION | 127 | 130 | /note="G4 #" | [NT]-K-x-D | 1 | |||||||
| REGION | 179 | 181 | /note="G5 #" | 1 | ||||||||
Additional information
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| Size range | 79-362 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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