ProRule PRU01103
General rule information
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| Accession | PRU01103 |
| Dates | 21-JUL-2015 (Created)
22-NOV-2019 (Last updated, Version 3) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51767; PEPTIDASE_A1 |
Name | Peptidase family A1 domain |
| Function | Eukaryotic aspartyl proteases (APs) form peptidase family A1 of clan AA. APs use an Asp dyad to hydrolyze peptide bonds. |
| Scope(s) |
Eukaryota |
| Example(s) | P32951 (CARP1_CANPA); |
Propagated annotation
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Comments
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| SIMILARITY | Belongs to the peptidase A1 family. |
Keywords
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| Aspartyl protease | |
| Hydrolase | |
| Protease | |
| end case | |
| case <FTTag:disulf> | |
| Disulfide bond | |
| end case | |
Gene Ontology
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| case <FTGroup:1> | |
| GO:0004190; Molecular function:aspartic-type endopeptidase activity | |
Cross-references
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| PROSITE | PS00141; ASP_PROTEASE; 2; |
Features
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| From: PS51767 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="Peptidase A1 #" | |||||||||
| ACT_SITE | 19 | 19 | D | 1 | ||||||||
| ACT_SITE | 204 | 204 | D | 1 | ||||||||
| DISULFID | 239 | 274 | disulf | C-x*-C | ||||||||
Additional information
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| Size range | 211-432 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [278] All [ 278 ]
- Retrieve set of proteins with 3D structure for this domain