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annotation rule: PRU01103

General rule information [?]

Accession PRU01103
Dates 21-JUL-2015 (Created)
22-NOV-2019 (Last updated, Version 3)
Data class Domain
Predictors PROSITE; PS51767; PEPTIDASE_A1
Name Peptidase family A1 domain
Function Eukaryotic aspartyl proteases (APs) form peptidase family A1 of clan AA. APs use an Asp dyad to hydrolyze peptide bonds.

Propagated annotation [?]

Comments [?]

Similarity Belongs to the peptidase A1 family.

Cross-references [?]


Gene Ontology [?]

case <FTGroup:1>
GO:0004190; Molecular function: aspartic-type endopeptidase activity.

Keywords [?]

end case

case <FTTag:disulf>
end case

Features [?]

From: PS51767
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       Peptidase A1 #        
ACT_SITE     19     19             D   1
ACT_SITE     204     204             D   1
DISULFID     239     274           disulf   C-x*-C  

Additional information [?]

Size range 211-432 amino acids
Related rules None
Repeats 1
Topology Undefined
Example P32951 (CARP1_CANPA)
Comments None


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]