![]() |
|
annotation rule: PRU01107 |
Accession | PRU01107 |
Dates | 21-AUG-2015 (Created) 3-JUN-2021 (Last updated, Version 6) |
Data class | Domain |
Predictors | PROSITE; PS51771; CGT_MARTX_CPD |
Name | CGT/MARTX cysteine protease (CPD) domain |
Function | The clostridial glucosylating toxins (CGTs) produced by Gram- positive bacteria and the multifunctional-autoprocessing RTX (MARTX) toxins of Gram-negative bacteria carry an embedded cysteine protease domain (CPD) that is regulated by a unique allosteric activation mechanism. The CGT/MARTX CPD catalytic dyad is composed of one His and one Cys residue. |
From: PS51771 | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
DOMAIN | from | to | Peptidase C80 # | |||||||||
ACT_SITE | 72 | 72 | H | 1 | ||||||||
ACT_SITE | 116 | 116 | Nucleophile | C | 1 |
Size range | 198-218 amino acids |
Related rules | None |
Repeats | 1 |
Topology | Undefined |
Example | Q9KS12 (MARTX_VIBCH) |
Scope | Bacteria; Peptoclostridium |
Comments | None |
Bacteria | [9] |