We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU01120
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01120
General rule information
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| Accession | PRU01120 |
| Dates | 04-DEC-2015 (Created)
22-NOV-2019 (Last updated, Version 4) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51784; EXOI_SH3 |
Name | Exonuclease I (ExoI) SH3-like domain |
| Function | Exonuclease I (ExoI) consists of three domains: an N-terminal nuclease domain with homology to the proofreading domain of E. coli DNA polymereae I and other DnaQ superfamily enzymes, a central domain with a portion that resembles an SH3 domain fold and a C-terminal alpha-helical domain. |
| Scope(s) |
Bacteria Gammaproteobacteria |
| Example(s) | Q89A43; |
Propagated annotation
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Features
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| From: PS51784 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="ExoI SH3-like #" | |||||||||
Additional information
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| Size range | 139-166 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Bacteria [5] All [ 5 ]
- Retrieve set of proteins with 3D structure for this domain