ProRule PRU01126
General rule information
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Accession | PRU01126 |
Dates | 10-FEB-2016 (Created)
19-NOV-2022 (Last updated, Version 7) |
Data class | Domain; |
Predictors |
PROSITE; PS51790; MSRB |
Name | Methionine-R-sulfoxide reductase (MsrB) domain |
Function | MsrB catalyzes the reduction of methionine-R-sulfoxide back to methionine. |
Scope(s) |
Bacteria Eukaryota |
Example(s) | A8A0X0 (MSRB_ECOHS); |
Propagated annotation
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Identifier, protein and gene names
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case <FTTag:Cat> | |
Protein name | + RecName: EC=1.8.4.-; |
end case |
Comments
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SIMILARITY | Belongs to the MsrB Met sulfoxide reductase family. |
Keywords
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Oxidoreductase | |
end case | |
case <FTGroup:1> | |
Metal-binding | |
Zinc | |
end case |
Gene Ontology
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case <FTGroup:1> | |
GO:0008270; Molecular function:zinc ion binding | |
end case | |
case <FTTag:Cat> | |
GO:0033743; Molecular function:peptide-methionine (R)-S-oxide reductase activity | |
GO:0006979; Biological process:response to oxidative stress |
Features
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From: PS51790 | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
DOMAIN | from | to | /note="MsrB #" | |||||||||
ACT_SITE | 112 | 112 | /note="Nucleophile" | Cat | [CU] | |||||||
BINDING | 40 | 40 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | 1 | |||||||
BINDING | 43 | 43 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | 1 | |||||||
BINDING | 89 | 89 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | 1 | |||||||
BINDING | 92 | 92 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | 1 |
Additional information
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Size range | 94-145 amino acids |
Related rules |
None |
Fusion | None |
Repeats | 1 |
Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Archaea [3] Bacteria [208] Eukaryota [30] All [ 241 ]
- Retrieve set of proteins with 3D structure for this domain