PRU01126

General rule information [?]

Accession	PRU01126
Dates	10-FEB-2016 (Created) 19-NOV-2022 (Last updated, Version 7)

Data class

Domain

Predictors

PROSITE; PS51790; MSRB

Name	Methionine-R-sulfoxide reductase (MsrB) domain

Function

MsrB catalyzes the reduction of methionine-R-sulfoxide back to methionine.

Propagated annotation [?]

Description [?]

case <FTTag:Cat>

+ RecName: EC 1.8.4.-;

end case

Comments [?]

Similarity

Belongs to the MsrB Met sulfoxide reductase family.

Gene Ontology [?]

case <FTGroup:1>

GO:0008270; Molecular function: zinc ion binding.

end case

case <FTTag:Cat>

GO:0033743; Molecular function: peptide-methionine (R)-S-oxide reductase activity.
GO:0006979; Biological process: response to oxidative stress.

Keywords [?]

Oxidoreductase

end case

case <FTGroup:1>

Metal-binding
Zinc

end case

Features [?]

From: PS51790

Key From To Description Tag Condition FTGroup

DOMAIN from to MsrB #

ACT_SITE 112 112 Nucleophile Cat [CU]

BINDING 40 40 /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105 C 1

BINDING 43 43 /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105 C 1

BINDING 89 89 /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105 C 1

BINDING 92 92 /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105 C 1

Additional information [?]

Size range	94-145 amino acids
Related rules	None
Repeats	1
Topology	Undefined
Example	A8A0X0 (MSRB_ECOHS)
Scope	Bacteria Eukaryota
Comments	None

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

View rule in raw text format (no links)

UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets

Archaea [3]

Bacteria [208]

Eukaryota [30]

All [ 241 ]
Retrieve set of proteins with 3D structure for this domain

Archaea	[3]
Bacteria	[208]
Eukaryota	[30]
All	[ 241 ]