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ProRule PRU01126


General rule information [?]

PURL https://purl.expasy.org/prosite/rule/PRU01126
Accession PRU01126
Dates 10-FEB-2016 (Created)
19-NOV-2022 (Last updated, Version 7)
Data class Domain;
Predictors PROSITE; PS51790; MSRB
Name Methionine-R-sulfoxide reductase (MsrB) domain
Function MsrB catalyzes the reduction of methionine-R-sulfoxide back to methionine.
Scope(s) Bacteria
Eukaryota
Example(s) A8A0X0 (MSRB_ECOHS);

Propagated annotation [?]

Identifier, protein and gene names [?]

case <FTTag:Cat>
Protein name + RecName: EC=1.8.4.-;
end case

Comments [?]

SIMILARITYBelongs to the MsrB Met sulfoxide reductase family.

Keywords [?]

Oxidoreductase
end case
case <FTGroup:1>
Metal-binding
Zinc
end case

Gene Ontology [?]

case <FTGroup:1>
GO:0008270; Molecular function:zinc ion binding
end case
case <FTTag:Cat>
GO:0033743; Molecular function:peptide-methionine (R)-S-oxide reductase activity
GO:0006979; Biological process:response to oxidative stress

Features [?]

From: PS51790
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="MsrB #"
ACT_SITE 112 112 /note="Nucleophile" Cat [CU]
BINDING 40 40 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"		 C 1
BINDING 43 43 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"		 C 1
BINDING 89 89 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"		 C 1
BINDING 92 92 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"		 C 1

Additional information [?]

Size range 94-145 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

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UniProtKB rule member sequences [?]