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annotation rule: PRU01133

General rule information [?]

Accession PRU01133
Dates 9-MAY-2016 (Created)
22-NOV-2019 (Last updated, Version 3)
Data class Domain
Predictors PROSITE; PS51797; TCTP_3
Name Translationally controlled tumor protein (TCTP) domain
Function The translationally controlled tumor proteins (TCTPs, such as p21, p23 and histamine releasing factor (HRF)) are a highly conserved and abundantly expressed family of eukaryotic proteins that are implicated in a variety of cellular functions, including microtubule stabilization, cell cycle, apoptosis, and cytokine release.

Propagated annotation [?]

Comments [?]

Similarity Belongs to the TCTP family.

Cross-references [?]

PROSITE PS01002; TCTP_1; 1;
PS01003; TCTP_2; 1;

Features [?]

From: PS51797
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       TCTP #        

Additional information [?]

Size range 10-204 amino acids
Related rules None
Repeats 1
Topology Undefined
Comments None


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]