ProRule PRU01133
General rule information
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| PURL | https://purl.expasy.org/prosite/rule/PRU01133 |
| Accession | PRU01133 |
| Dates | 9-MAY-2016 (Created)
22-NOV-2019 (Last updated, Version 3) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51797; TCTP_3 |
Name | Translationally controlled tumor protein (TCTP) domain |
| Function | The translationally controlled tumor proteins (TCTPs, such as p21, p23 and histamine releasing factor (HRF)) are a highly conserved and abundantly expressed family of eukaryotic proteins that are implicated in a variety of cellular functions, including microtubule stabilization, cell cycle, apoptosis, and cytokine release. |
| Scope(s) |
Eukaryota |
| Example(s) | Q7RYV5 (TCTP_NEUCR); |
Propagated annotation
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Comments
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| SIMILARITY | Belongs to the TCTP family. |
Cross-references
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Features
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| From: PS51797 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="TCTP #" | |||||||||
Additional information
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| Size range | 10-204 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [89] All [ 89 ]
- Retrieve set of proteins with 3D structure for this domain