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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU01133


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01133
General rule information [?]

Accession PRU01133
Dates 09-MAY-2016 (Created)
22-NOV-2019 (Last updated, Version 4)
Data class Domain;
Predictors PROSITE; PS51797; TCTP_3
Name Translationally controlled tumor protein (TCTP) domain
Function The translationally controlled tumor proteins (TCTPs, such as p21, p23 and histamine releasing factor (HRF)) are a highly conserved and abundantly expressed family of eukaryotic proteins that are implicated in a variety of cellular functions, including microtubule stabilization, cell cycle, apoptosis, and cytokine release.
Scope(s) Eukaryota
Example(s) Q7RYV5;

Propagated annotation [?]

Comments [?]

SIMILARITYBelongs to the TCTP family.

Cross-references [?]

PROSITE PS01002; TCTP_1; 1;
PROSITE PS01003; TCTP_2; 1;

Features [?]

From: PS51797
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="TCTP #"

Additional information [?]

Size range 10-204 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]