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| annotation rule: PRU01140 |
General rule information
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| Accession | PRU01140 |
| Dates | 24-MAY-2016 (Created) 22-NOV-2019 (Last updated, Version 3) |
| Data class | Domain |
| Predictors | PROSITE; PS51799; ZF_C2H2_AKAP95 |
| Name | Zinc finger C2H2 AKAP95-type |
| Function | AKAP95 harbours two zinc fingers, designated ZF1 and ZF2. ZF1 mediates the binding of AKAP95 to DNA. ZF2 is dispensable for chromatin binding; however it may substitute for ZF1 when the latter is rendered non- functional by mutation. |
Propagated annotation
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Comments
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| Similarity | Belongs to the AKAP95 family. |
Keywords
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case <Feature:PS51799:1=[CH]> and <Feature:PS51799:4=[CH]> and <Feature:PS51799:18=[CH]> and <Feature:PS51799:24=[CH]>
end case
Features
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case <Feature:PS51799:1=[C]> and <Feature:PS51799:4=[C]> and <Feature:PS51799:18=[H]> and <Feature:PS51799:24=[H]>
| From: PS51799 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ZN_FING | from | to | C2H2 AKAP95-type # | |||||||||
else case <Feature:PS51799:1=[CH]> and <Feature:PS51799:4=[CH]> and <Feature:PS51799:18=[CH]> and <Feature:PS51799:24=[CH]>
else
end case
Additional information
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| Size range | 13-34 amino acids |
| Related rules | None |
| Repeats | 2 |
| Topology | Undefined |
| Example | O88291 (ZN326_MOUSE) |
| Scope | Eukaryota; Euteleostomi |
| Comments | None |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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